Compile Data Set for Download or QSAR
maximum 50k data
Found 37 of kd for UniProtKB: P10275
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataKd:  0.25nMAssay Description:Binding affinity to human Androgen receptorMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to human Androgen receptorMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKd:  0.520nMAssay Description:Dissociation constant for [3H]R-1881 binding to human androgen receptor at 278 KMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKd:  0.560nMAssay Description:Dissociation constant for [3H]R-1881 binding to human androgen receptor at 283 KMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKd:  0.600nMAssay Description:Binding affinity to androgen receptorMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKd:  0.610nMAssay Description:Dissociation constant for [3H]R-1881 binding to human androgen receptor at 273 KMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKd:  0.680nMAssay Description:Dissociation constant for [3H]R-1881 binding to human androgen receptor at 288 KMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKd:  0.740nMAssay Description:Dissociation constant value of the radiolabeled compound against the androgen receptor 293 KMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKd:  0.990nMAssay Description:Dissociation constant for [3H]R-1881 binding to human androgen receptor at 298 KMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataKd:  1nMAssay Description:Agonist activity at human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKd:  1.21nMAssay Description:Dissociation constant for [3H]R-1881 binding to human androgen receptor at 303 KMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50131272(3-(4-Fluoro-phenyl)-4-[1-(4-pyrrolidin-1-yl-phenyl...)
Affinity DataKd:  1.40nMAssay Description:Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]-testosterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50131271(3-(4-Hydroxy-phenyl)-4-[1-(4-pyrrolidin-1-yl-pheny...)
Affinity DataKd:  1.40nMAssay Description:Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]-testosterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50131269(3-(2-Fluoro-phenyl)-4-[1-(4-pyrrolidin-1-yl-phenyl...)
Affinity DataKd:  1.40nMAssay Description:Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]-testosterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50131268(4-[1-(4-Dibutylamino-phenyl)-meth-(Z)-ylidene]-3-p...)
Affinity DataKd:  1.40nMAssay Description:Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]-testosterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKd:  1.51nMAssay Description:Dissociation constant for [3H]R-1881 binding to human androgen receptor at 308 KMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataKd:  1.95nMAssay Description:Dissociation constant for [3H]R-1881 binding to human androgen receptor at 310KMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM334273(2-Butyl-2- hydroxy-hexanoic acid (2-bromo- pyridin...)
Affinity DataKd:  15nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM334276(2-Hydroxy-2,4- dimethyl-pentanoic acid (2-bromo-6-...)
Affinity DataKd:  20nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM334272(2-Hydroxy-2- methyl-hexanoic acid (2-bromo- 6-meth...)
Affinity DataKd:  30nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM334271(2-Hydroxy-2- methyl- pentanoic acid (2-bromo-pyrid...)
Affinity DataKd:  75nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM334275(N-(2-Bromo- pyridin-4-yl)-2- hydroxy-2-phenyl- pro...)
Affinity DataKd:  100nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM334277(N-(2-Bromo-pyridin- 4-yl)-2-hydroxy- 2-methyl-4-ph...)
Affinity DataKd:  100nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM334274(N-(2-Bromo-pyridin- 4-yl)-2-hydroxy-4- (4-methoxy-...)
Affinity DataKd:  300nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50529667(CHEMBL4444904 | US10806720, Compound 11 | US112305...)
Affinity DataKd:  1.30E+3nMAssay Description:Inhibition of androgen receptor AF1 domain (141 to 486 residues) (unknown origin) incubated for 30 mins by steady-state fluorescence emission spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor [646-919](Homo sapiens (Human))
Karlsruhe Institute Of Technology

LigandPNGBDBM227645(Bag-1L (1-20) | MAQRGGARRPRGDRERLGSR)
Affinity DataKd:  2.00E+3nMpH: 6.5Assay Description:For the fluorescence polarization experiments, 5 nM fluorescently labeled Bag-1L (Bag-1L(1-20), fluorescein isothiocyanate (FITC)-MAQRGGARRPRGDRERLGS...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor [646-919](Homo sapiens (Human))
Karlsruhe Institute Of Technology

LigandPNGBDBM227647(HDSKGQTKLLQLLTTKSDQM | SCR-2 peptide)
Affinity DataKd:  2.80E+3nMpH: 6.5Assay Description:For the fluorescence polarization experiments, 5 nM fluorescently labeled Bag-1L (Bag-1L(1-20), fluorescein isothiocyanate (FITC)-MAQRGGARRPRGDRERLGS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor [646-919](Homo sapiens (Human))
Karlsruhe Institute Of Technology

LigandPNGBDBM227646(Bag-1L (61-80) | RGAAAGARRPRMKKKTRRRS)
Affinity DataKd:  3.30E+3nMpH: 6.5Assay Description:For the fluorescence polarization experiments, 5 nM fluorescently labeled Bag-1L (Bag-1L(1-20), fluorescein isothiocyanate (FITC)-MAQRGGARRPRGDRERLGS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM334278(4-(2-Hydroxy-2- methyl- pentanoylamino)- pyridine-...)
Affinity DataKd:  6.00E+3nMAssay Description:The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50425732(ENZALUTAMIDE | US10053433, FC 4.129 | US10806720, ...)
Affinity DataKd:  6.52E+3nMAssay Description:Binding affinity to full length androgen receptor (unknown origin) assessed as dissociation constant at 5 uM measured after 15 mins by biolayer inter...More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50589959(CHEMBL5203294)
Affinity DataKd:  8.99E+3nMAssay Description:Binding affinity to full length androgen receptor (unknown origin) assessed as dissociation constant at 5 uM measured after 15 mins by biolayer inter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50589954(CHEMBL5177079)
Affinity DataKd:  1.01E+4nMAssay Description:Binding affinity to full length androgen receptor (unknown origin) assessed as dissociation constant at 5 uM measured after 15 mins by biolayer inter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50589964(CHEMBL5201101)
Affinity DataKd:  2.05E+4nMAssay Description:Binding affinity to full length androgen receptor (unknown origin) assessed as dissociation constant at 5 uM measured after 15 mins by biolayer inter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50425732(ENZALUTAMIDE | US10053433, FC 4.129 | US10806720, ...)
Affinity DataKd:  4.02E+4nMAssay Description:Binding affinity to human AR LBD (663 to 920 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant by biolayer interfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50584670(CHEMBL5085066)
Affinity DataKd:  7.59E+4nMAssay Description:Binding affinity to human AR LBD (663 to 920 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant in presence of DHT ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50425732(ENZALUTAMIDE | US10053433, FC 4.129 | US10806720, ...)
Affinity DataKd:  2.95E+5nMAssay Description:Binding affinity to human AR LBD (663 to 920 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant in presence of DHT ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50584670(CHEMBL5085066)
Affinity DataKd:  7.60E+7nMAssay Description:Binding affinity to human AR LBD (663 to 920 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant by biolayer interfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed