TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 0.0310nMAssay Description:Inhibition of human CAMK2A using KKALRRQETVDAL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of human CAMK2A using KKALRRQETVDAL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1nMAssay Description:Inhibition of CamK2alphaMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant full length CAMK2alpha (unknown origin) using autocamtide-2 as substrate assessed as incorporation of 32P after 30 mins by ...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant full length CAMK2alpha (unknown origin) using autocamtide-2 as substrate assessed as incorporation of 32P after 30 mins by ...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant full length CAMK2alpha (unknown origin) using autocamtide-2 as substrate assessed as incorporation of 32P after 30 mins by ...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of autophosphorylated alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 min in prese...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of autophosphorylated alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 min in prese...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of human CaMKIIalpha using calmodulin and syntide-2 incubated for 15 mins by ELISAMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Inhibition of human CaMKIIalpha using calmodulin and syntide-2 incubated for 15 mins by ELISAMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of human CaMKIIalpha using calmodulin and syntide-2 incubated for 15 mins by ELISAMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CaMK2a (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CAMK2alpha (unknown origin)More data for this Ligand-Target Pair
Ligand Info
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human CaMKIIalpha using calmodulin and syntide-2 incubated for 15 mins by ELISAMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 minMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 1.81E+3nMAssay Description:Binding affinity to recombinant human CaMK2alpha 6x hub domain (345 to 475 residues) Trp403 residue assessed as inhibition of intrinsic tryptophan fl...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2alpha using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of autophosphorylated alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 minMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of alphaCaMK2 autophosphorylation at Thr286 using [gamma32P]ATP incubated for 30 secs prior to ATP addition measured after 30 secsMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CamK2alphaMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Agents: 1-fold kinase buffer without MnCl2: 50 mM HEPES, pH 7.5, 0.0015% Brij-35, 10 mM MgCl2, 2 mM DTT. 1-fold kinase buffer with MnCl2: 50 mM HEPES...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human alphaCaMK2 by CaM kinase 2 assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human CaMK2alpha using KKLNRTLSFAEPG as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiome...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CAMK2A (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CAMK2A (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CAMK2A (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CAMK2A (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CAMK2alpha using [KKLNRTLSFAEPG] as substrateMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 minMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 minMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of alphaCaMK2 autophosphorylation at Thr286 using [gamma32P]ATP incubated for 30 secs prior to ATP addition measured after 30 secsMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 minMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of autophosphorylated alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 minMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of alphaCaMK2 autophosphorylation at Thr286 using [gamma32P]ATP incubated for 30 secs prior to ATP addition measured after 30 secsMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of autophosphorylated alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 min in prese...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 minMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 minMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CAMK2AMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of autophosphorylated alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 minMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of autophosphorylated alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 min in prese...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of autophosphorylated alphaCaMK2 using GST-NR2A as substrate incubated for 1 min prior to substrate addition measured after 1 minMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of alphaCaMK2 autophosphorylation at Thr286 using [gamma32P]ATP incubated for 30 secs prior to ATP addition measured after 30 secsMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataIC50: 4.52E+5nMAssay Description:Binding affinity to recombinant human CaMK2alpha 6x hub domain (345 to 475 residues) Trp403 residue assessed as inhibition of intrinsic tryptophan fl...More data for this Ligand-Target Pair