Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50013771
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50426967(PF-4693627 | CHEMBL2325079)
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569446(CHEMBL4870406)
Affinity DataIC50: 490nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569442(CHEMBL4864480)
Affinity DataIC50: 610nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569443(CHEMBL4851179)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569445(CHEMBL4848316)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed