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Report error Found 4298 Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2'
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297400((S)-4-Cyano-N-[3-(4-fluorophenyl)-3-(4-methanesulf...)
Affinity DataEC50:  0.140nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297414(N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phenyl)...)
Affinity DataEC50:  0.300nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297400((S)-4-Cyano-N-[3-(4-fluorophenyl)-3-(4-methanesulf...)
Affinity DataEC50:  0.300nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297401(N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phenyl)...)
Affinity DataEC50:  0.400nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297399(N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phenyl)...)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297395((S)-N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phe...)
Affinity DataEC50:  2.10nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297403((R)-4-Cyano-N-[3-(4-fluorophenyl)-3-(4-methanesulf...)
Affinity DataEC50:  2.80nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305632(N-(2,4-dichlorobenzyl)-4-(4-fluorophenoxy)piperidi...)
Affinity DataEC50:  4.20nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305633(4-(4-chlorophenoxy)-N-(2,4-dichlorobenzyl)piperidi...)
Affinity DataEC50:  10nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305634(N-(2,4-dichlorobenzyl)-4-(4-(trifluoromethoxy)phen...)
Affinity DataEC50:  18nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305635(4-(2-cyanophenoxy)-N-(2,4-dichlorobenzyl)piperidin...)
Affinity DataEC50:  0.440nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305636(4-(3-cyanophenoxy)-N-(2,4-dichlorobenzyl)piperidin...)
Affinity DataEC50:  0.630nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305637(4-(4-cyanophenoxy)-N-(2,4-dichlorobenzyl)piperidin...)
Affinity DataEC50:  0.780nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305638(N-(2,4-dichlorobenzyl)-4-(2-(methylsulfonyl)phenox...)
Affinity DataEC50:  1.65nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305639(N-(2,4-dichlorobenzyl)-4-(3-(methylsulfonyl)phenox...)
Affinity DataEC50:  0.25nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305640(N-(2,4-dichlorobenzyl)-4-(4-(methylsulfonyl)phenox...)
Affinity DataEC50:  0.970nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305641(N-(2,4-dichlorobenzyl)-4-(4-(methylcarbamoyl)pheno...)
Affinity DataEC50:  0.340nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305642(N-(2,4-dichlorobenzyl)-4-(4-(N-methylsulfamoyl)phe...)
Affinity DataEC50:  0.290nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305643(4-(1-(2,4-dichlorobenzylcarbamoyl)piperidin-4-ylox...)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414746(CHEMBL2021563)
Affinity DataEC50:  23nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414745(CHEMBL2021549)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50583627(CHEMBL5075221)
Affinity DataEC50:  240nMAssay Description:Inhibition of recombinant human C-terminal sEH (222 to 555 residues) expressed in Escherichia coli BL21-DE3 using PHOME as substrate assessed as redu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594428(CHEMBL5192349)
Affinity DataKd:  6nMAssay Description:Binding affinity to NanoLuc-fused human sEH ( 1 to 555 residues) expressed in HEK293T cells incubated for 5 hrs by NanoBRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50264106(CHEMBL3818875)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of recombinant human sEH using MNPC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2020
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50264106(CHEMBL3818875)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50264106(CHEMBL3818875)
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of human recombinant sEH using 14,15-epoxy-5Z,8Z,11Z-eicosatrienoic acid as substrate assessed as formation of 14,15-dihydroxy-5Z,8Z,11Zei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50264106(CHEMBL3818875)
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of human recombinant sEH using 14,15-epoxy-5Z,8Z,11Z-eicosatrienoic acid as substrate assessed as formation of 14,15-dihydroxy-5Z,8Z,11Zei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50595239(CHEMBL5190894)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50631945(CHEMBL5425833)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631937(CHEMBL5415121)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631955(CHEMBL5427173)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50556773(CHEMBL4745610)
Affinity DataIC50: 0.0820nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate measured after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631928(CHEMBL5428998)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302462(N-(4-bromo-2-(trifluoromethoxy)benzyl)-6-(3,3,3-tr...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of soluble EH in human HepG2 cells by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50556760(CHEMBL4781218)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate measured after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631954(CHEMBL5430033)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631926(CHEMBL5424246)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631929(CHEMBL5435557)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631940(CHEMBL5433624)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM342631(5-[4-((R)-2-Hydroxy-propionyl)-piperazin-1-ylmethy...)
Affinity DataIC50: 0.122nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50445769(CHEMBL3104615)
Affinity DataIC50: 0.125nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenylox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631952(CHEMBL5433817)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631945(CHEMBL5425833)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50631928(CHEMBL5428998)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50631935(CHEMBL5403016)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631915(CHEMBL5405764)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631917(CHEMBL5422052)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631956(CHEMBL5431410)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM342634(5-[4-(Pyridine-3-carbonyl)-piperazin-1-ylmethyl]-t...)
Affinity DataIC50: 0.168nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631911(CHEMBL5396859)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
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