Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 3068
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Universita Di Siena

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  30nM ΔG°:  -44.7kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,V694A]/[588-1147,V694A](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  40nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,V767D]/[588-1147,V767D](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  100nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Universita Di Siena

LigandPNGBDBM27580(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Affinity DataKi:  100nM ΔG°:  -41.6kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Universita Di Siena

LigandPNGBDBM27582(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Affinity DataKi:  110nM ΔG°:  -41.3kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  120nM ΔG°:  -41.1kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,Y769I]/[588-1147,Y769I](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  150nM ΔG°:  -40.5kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  160nM ΔG°:  -40.3kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Universita Di Siena

LigandPNGBDBM27581(8-ethyl-8-[4-(phenoxymethyl)phenyl]-9-oxa-2,14-dia...)
Affinity DataKi:  250nM ΔG°:  -39.2kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27580(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Affinity DataKi:  250nM ΔG°:  -39.2kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,V767D]/[588-1147,V767D](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27580(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Affinity DataKi:  300nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27580(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Affinity DataKi:  300nM ΔG°:  -38.7kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,Y776L]/[588-1147,Y776L](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  380nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Universita Di Siena

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataKi:  400nM ΔG°:  -38.0kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27582(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Affinity DataKi:  800nM ΔG°:  -36.2kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27582(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Affinity DataKi:  800nM ΔG°:  -36.2kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27581(8-ethyl-8-[4-(phenoxymethyl)phenyl]-9-oxa-2,14-dia...)
Affinity DataKi:  1.50E+3nM ΔG°:  -34.6kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,V694A]/[588-1147,V694A](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27581(8-ethyl-8-[4-(phenoxymethyl)phenyl]-9-oxa-2,14-dia...)
Affinity DataKi:  1.80E+3nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,V767D]/[588-1147,V767D](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataKi:  2.00E+3nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,V767D]/[588-1147,V767D](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27582(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Affinity DataKi:  2.00E+3nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,V767D]/[588-1147,V767D](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27581(8-ethyl-8-[4-(phenoxymethyl)phenyl]-9-oxa-2,14-dia...)
Affinity DataKi:  3.60E+3nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataKi:  7.00E+3nM ΔG°:  -30.6kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataKi:  9.00E+3nM ΔG°:  -30.0kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,V694A]/[588-1147,V694A](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataKi:  1.00E+4nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,Y769I]/[588-1147,Y769I](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27582(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Affinity DataKi: <1.00E+4nM ΔG°: <-29.7kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,Y769I]/[588-1147,Y769I](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27581(8-ethyl-8-[4-(phenoxymethyl)phenyl]-9-oxa-2,14-dia...)
Affinity DataKi: <1.00E+4nM ΔG°: <-29.7kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,Y769I]/[588-1147,Y769I](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27580(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Affinity DataKi: <1.00E+4nM ΔG°: <-29.7kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,Y776L]/[588-1147,Y776L](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM27581(8-ethyl-8-[4-(phenoxymethyl)phenyl]-9-oxa-2,14-dia...)
Affinity DataKi: <1.00E+4nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,Y776L]/[588-1147,Y776L](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataKi:  1.80E+4nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,Y769I]/[588-1147,Y769I](Human immunodeficiency virus type 1)
Universita Di Siena

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataKi:  3.60E+4nM ΔG°:  -26.4kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair