Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50016219
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161093BDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166511BDBM50166511(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 95nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166504BDBM50166504(5-Ethyl-3-[2-(2-fluoro-phenyl)-ethyl]-2-(2-hydroxy...)
Affinity DataIC50: 97nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166510BDBM50166510(5-Ethyl-2-(2-hydroxy-phenyl)-6-methyl-3-phenethyl-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166517BDBM50166517(5-Cyclopropyl-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-h...)
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166507BDBM50166507(2-(2-Hydroxy-phenyl)-3-phenethyl-4a,5,6,7,8,8a-hex...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166503BDBM50166503(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166505BDBM50166505(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166512BDBM50166512(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166509BDBM50166509(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166508BDBM50166508(2-(2-Hydroxy-phenyl)-3-phenethyl-3,4a,5,6,7,7a-hex...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166514BDBM50166514(2-(2-Hydroxy-phenyl)-5,6-dimethyl-3-phenethyl-3H-p...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166516BDBM50166516(2-(2-Hydroxy-phenyl)-5-methyl-3-phenethyl-6-triflu...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166506BDBM50166506(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166515BDBM50166515(3-[2-(2-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166513BDBM50166513(2-(2-Hydroxy-phenyl)-6-methyl-3-phenethyl-3H-pyrim...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162542BDBM50162542(2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one | CHE...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed