Compile Data Set for Download or QSAR
Report error Found 127 Enz. Inhib. hit(s) with all data for entry = 50018414
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195506((4-amino-3,5-dichloro-phenyl)-(2-aza-tricyclo[3.3....)
Affinity DataKi:  4nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195504((4-amino-3,5-dichlorophenyl)(1,3,3-trimethyl-6-aza...)
Affinity DataKi:  4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195506((4-amino-3,5-dichloro-phenyl)-(2-aza-tricyclo[3.3....)
Affinity DataKi:  4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195481((1s,4s)-ethyl 4-(4-amino-3,5-dichloro-N-cyclopropy...)
Affinity DataKi:  4nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195497((4-amino-3,5-dichlorophenyl)((2R,6S)-4-(3-aminopyr...)
Affinity DataKi:  5nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195489(4-amino-3,5-dichloro-N-cyclopropyl-N-((1s,4s)-4-(p...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195485(4-amino-3,5-dichloro-N-cyclohexyl-N-cyclopropylben...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195482((4-amino-3,5-dichlorophenyl)((2R,6S)-2,6-dimethyl-...)
Affinity DataKi:  6nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195483(N-adamantan-1-yl-4-amino-3,5-dichloro-N-methyl-ben...)
Affinity DataKi:  6nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195487(4-amino-3,5-dichloro-N-cyclopentyl-N-cyclopropylbe...)
Affinity DataKi:  8nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195504((4-amino-3,5-dichlorophenyl)(1,3,3-trimethyl-6-aza...)
Affinity DataKi:  8nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195493(4-amino-3,5-dichloro-N-cyclopropyl-N-((1s,4s)-4-(1...)
Affinity DataKi:  9nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195483(N-adamantan-1-yl-4-amino-3,5-dichloro-N-methyl-ben...)
Affinity DataKi:  10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195499((4-amino-3,5-dichlorophenyl)((2R,6S)-4-(2-methoxyp...)
Affinity DataKi:  10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195495(3-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataKi:  12nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195486(ethyl 2-((3R,5S)-4-(4-amino-3,5-dichlorobenzoyl)-3...)
Affinity DataKi:  13nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195492(3-((2R,4R)-1-(4-amino-3,5-dichlorobenzoyl)-2-methy...)
Affinity DataKi:  13nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195486(ethyl 2-((3R,5S)-4-(4-amino-3,5-dichlorobenzoyl)-3...)
Affinity DataKi:  14nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195485(4-amino-3,5-dichloro-N-cyclohexyl-N-cyclopropylben...)
Affinity DataKi:  14nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195498(methyl 2-((1s,4s)-4-(4-amino-3,5-dichloro-N-cyclop...)
Affinity DataKi:  14nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195497((4-amino-3,5-dichlorophenyl)((2R,6S)-4-(3-aminopyr...)
Affinity DataKi:  15nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195491((4-amino-3,5-dichlorophenyl)(3-benzyl-3,6-diaza-bi...)
Affinity DataKi:  16nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195487(4-amino-3,5-dichloro-N-cyclopentyl-N-cyclopropylbe...)
Affinity DataKi:  16nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195503(4-amino-N-((1s,4s)-4-(benzylcarbamoyl)cyclohexyl)-...)
Affinity DataKi:  17nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195504((4-amino-3,5-dichlorophenyl)(1,3,3-trimethyl-6-aza...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195488(N-((1s,4s)-4-((2-(dimethylamino)ethyl)carbamoyl)cy...)
Affinity DataKi:  17nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195499((4-amino-3,5-dichlorophenyl)((2R,6S)-4-(2-methoxyp...)
Affinity DataKi:  18nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195505(ethyl 2-((3R,5S)-4-(4-amino-3,5-dichlorobenzoyl)-3...)
Affinity DataKi:  19nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195502(N-((1s,4s)-4-((cyclohexylmethyl)carbamoyl)cyclohex...)
Affinity DataKi:  20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195490(2-((1s,4s)-4-(4-amino-3,5-dichloro-N-cyclopropylbe...)
Affinity DataKi:  20nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195484(1-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataKi:  22nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195505(ethyl 2-((3R,5S)-4-(4-amino-3,5-dichlorobenzoyl)-3...)
Affinity DataKi:  23nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195481((1s,4s)-ethyl 4-(4-amino-3,5-dichloro-N-cyclopropy...)
Affinity DataKi:  28nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195496((4-amino-3,5-dichlorophenyl)((2R,6S)-2,6-dimethylp...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195503(4-amino-N-((1s,4s)-4-(benzylcarbamoyl)cyclohexyl)-...)
Affinity DataKi:  39nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195484(1-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataKi:  39nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195506((4-amino-3,5-dichloro-phenyl)-(2-aza-tricyclo[3.3....)
Affinity DataIC50: 41nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195494((4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan...)
Affinity DataKi:  53nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195498(methyl 2-((1s,4s)-4-(4-amino-3,5-dichloro-N-cyclop...)
Affinity DataKi:  60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195502(N-((1s,4s)-4-((cyclohexylmethyl)carbamoyl)cyclohex...)
Affinity DataKi:  68nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195495(3-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195484(1-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195483(N-adamantan-1-yl-4-amino-3,5-dichloro-N-methyl-ben...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195482((4-amino-3,5-dichlorophenyl)((2R,6S)-2,6-dimethyl-...)
Affinity DataKi:  100nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195485(4-amino-3,5-dichloro-N-cyclohexyl-N-cyclopropylben...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195489(4-amino-3,5-dichloro-N-cyclopropyl-N-((1s,4s)-4-(p...)
Affinity DataKi:  130nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195487(4-amino-3,5-dichloro-N-cyclopentyl-N-cyclopropylbe...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195492(3-((2R,4R)-1-(4-amino-3,5-dichlorobenzoyl)-2-methy...)
Affinity DataKi:  140nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195495(3-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataKi:  160nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195499((4-amino-3,5-dichlorophenyl)((2R,6S)-4-(2-methoxyp...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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