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Found 18 Enz. Inhib. hit(s) with all data for entry = 50030420
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295892((Z)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-3-(4-ni...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295893((Z)-3-(4-chlorophenyl)-5-(4-hydroxy-3,5-dimethoxyb...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295894((Z)-3-(3-chlorophenyl)-5-(4-hydroxy-3,5-dimethoxyb...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM11994(2-{[4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl]sulfanyl...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM11985(4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic a...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295891((Z)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-2-thiox...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295886(4-(2-methylthiazol-4-yl)-1H-pyrrole-2-carboxylic a...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295897(6,7-dihydroxy-4-((1-methyl-1H-benzo[d]imidazol-2-y...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295895(3,4,5-trimethoxy-N-(6-(morpholinosulfonyl)benzo[d]...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295898(4-((4-amino-5-(2-fluorobenzyl)-4H-1,2,4-triazol-3-...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295889(6-(benzofuran-2-yl)-N2-(4-methoxyphenyl)-1,3,5-tri...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM34851(3-benzyl-7,8-dihydroxy-4-methyl-2H-chromen-2-one |...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295890(CHEMBL558246 | N-(4-(N-(3,4-dimethylisoxazol-5-yl)...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295896(2-ethoxy-N-(6-sulfamoylbenzo[d]thiazol-2-yl)benzam...)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295899(3-(4,8-dimethyl-7-(naphthalen-1-ylmethoxy)-2-oxo-2...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295887(6-ethyl-9-mercapto-6-methyl-5,6-dihydrobenzo[h][1,...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295888(2-(5-(5-mercapto-1,3,4-oxadiazol-2-yl)furan-2-yl)b...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295900(3-(7-(4-bromo-2-fluorobenzyloxy)-4,8-dimethyl-2-ox...)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed