Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50040231
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240618BDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  3.98nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240618BDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colonic longitudinal muscle/myenteric plexus assessed as contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388698BDBM50388698(CHEMBL2059590)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391069BDBM50391069(TD-5108 | VELUSETRAG)
Affinity DataEC50:  12.6nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colonic longitudinal muscle/myenteric plexus assessed as contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388687BDBM50388687(CHEMBL538635)
Affinity DataKi:  12.6nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391074BDBM50391074(CHEMBL2087326)
Affinity DataKi:  15.8nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391065BDBM50391065(CHEMBL2087336)
Affinity DataKi:  19.9nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391068BDBM50391068(CHEMBL2087334)
Affinity DataKi:  19.9nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391069BDBM50391069(TD-5108 | VELUSETRAG)
Affinity DataKi:  19.9nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391067BDBM50391067(CHEMBL2087328)
Affinity DataKi:  25.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391070BDBM50391070(CHEMBL2087324)
Affinity DataKi:  31.6nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391073BDBM50391073(CHEMBL2087333)
Affinity DataKi:  39.8nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391066BDBM50391066(CHEMBL2087325)
Affinity DataKi:  39.8nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391072BDBM50391072(CHEMBL2087327)
Affinity DataKi:  50.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391063BDBM50391063(CHEMBL2087331)
Affinity DataKi:  50.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391065BDBM50391065(CHEMBL2087336)
Affinity DataKi:  50.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391064BDBM50391064(CHEMBL2087332)
Affinity DataKi:  50.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391071BDBM50391071(CHEMBL2087329)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388686BDBM50388686(CHEMBL74656)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391062BDBM50391062(CHEMBL2087330)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed