Compile Data Set for Download or QSAR
maximum 50k data
Found 92 Enz. Inhib. hit(s) with all data for entry = 50044305
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50130563((3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphe...)
Affinity DataKi:  0.0200nMAssay Description:Antagonist activity at kappa opioid receptor in guinea pig caudate assessed as inhibition of U69593-stimulated [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50350976(CHEMBL1818341)
Affinity DataKi:  1.20nMAssay Description:Antagonist activity at human cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of U69593-stimulated [35S]-GTP[gammaS] bindin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012152(CHEMBL3264441)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]diprenorphine from kappa opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50130563((3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphe...)
Affinity DataKi:  2.20nMAssay Description:Antagonist activity at mu opioid receptor in guinea pig caudate assessed as inhibition of DAMGO-stimulated [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012151(CHEMBL3264440)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]diprenorphine from mu opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50350976(CHEMBL1818341)
Affinity DataKi:  10nMAssay Description:Antagonist activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012151(CHEMBL3264440)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]diprenorphine from kappa opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012152(CHEMBL3264441)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]diprenorphine from mu opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012153(zyklophin)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]diprenorphine from kappa opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012150(CHEMBL3264439)
Affinity DataKi:  159nMAssay Description:Displacement of [3H]diprenorphine from kappa opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012150(CHEMBL3264439)
Affinity DataKi:  186nMAssay Description:Displacement of [3H]diprenorphine from mu opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012151(CHEMBL3264440)
Affinity DataKi:  221nMAssay Description:Displacement of [3H]diprenorphine from delta opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012150(CHEMBL3264439)
Affinity DataKi:  475nMAssay Description:Displacement of [3H]diprenorphine from delta opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71610(KSC-1-256 | KUC104502N | ML190 | cid_44665680)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to muscarinic M2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM75566(KSC-11-114-1 | KUC105392N | N-[2-[benzyl(tert-buty...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to muscarinic M2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to muscarinic M3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM75566(KSC-11-114-1 | KUC105392N | N-[2-[benzyl(tert-buty...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to muscarinic M3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to muscarinic M4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM75566(KSC-11-114-1 | KUC105392N | N-[2-[benzyl(tert-buty...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to muscarinic M4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71610(KSC-1-256 | KUC104502N | ML190 | cid_44665680)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma-1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM75566(KSC-11-114-1 | KUC105392N | N-[2-[benzyl(tert-buty...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma-1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71610(KSC-1-256 | KUC104502N | ML190 | cid_44665680)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to adrenergic alpha2C receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012152(CHEMBL3264441)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [3H]diprenorphine from delta opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71610(KSC-1-256 | KUC104502N | ML190 | cid_44665680)
Affinity DataIC50:  3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by high content imaging beta-arrestin translocation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71613(KSC-1-265 | KUC104505N | cid_44665679)
Affinity DataIC50:  4nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by high content imaging beta-arrestin translocation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012149(CHEMBL3264446 | US10118915, Compound 105 | US96829...)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of U69593-stimulated [35S]-GTP[gammaS] bindin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM75566(KSC-11-114-1 | KUC105392N | N-[2-[benzyl(tert-buty...)
Affinity DataIC50:  30nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by high content imaging beta-arrestin translocation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM75566(KSC-11-114-1 | KUC105392N | N-[2-[benzyl(tert-buty...)
Affinity DataIC50:  60nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by DiscoveryRx b-arrestin PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71611(KSC-1-261 | KUC104503N | cid_44665687)
Affinity DataIC50:  70nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by high content imaging beta-arrestin translocation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71610(KSC-1-256 | KUC104502N | ML190 | cid_44665680)
Affinity DataIC50:  120nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by DiscoveryRx b-arrestin PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71613(KSC-1-265 | KUC104505N | cid_44665679)
Affinity DataIC50:  190nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by DiscoveryRx b-arrestin PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012149(CHEMBL3264446 | US10118915, Compound 105 | US96829...)
Affinity DataIC50:  343nMAssay Description:Antagonist activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012148(CHEMBL3183148)
Affinity DataIC50:  376nMAssay Description:Antagonist activity at human cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of U69593-stimulated [35S]-GTP[gammaS] bindin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71581(KSC-5-280C | KUC104162N | N-[2-[(4-bromobenzyl)-is...)
Affinity DataIC50:  570nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by high content imaging beta-arrestin translocation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71581(KSC-5-280C | KUC104162N | N-[2-[(4-bromobenzyl)-is...)
Affinity DataIC50:  660nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by DiscoveryRx b-arrestin PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71611(KSC-1-261 | KUC104503N | cid_44665687)
Affinity DataIC50:  690nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by DiscoveryRx b-arrestin PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM71619(KSC-1-278 | KUC104646N | cid_45100475)
Affinity DataIC50:  700nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by high content imaging beta-arrestin translocation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataIC50:  860nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by high content imaging beta-arrestin translocation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54817(4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...)
Affinity DataIC50:  860nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by DiscoveryRx b-arrestin PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM65828(4-[[(4-ethylphenyl)sulfonylamino]methyl]-N-[2-[(ph...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by DiscoveryRx b-arrestin PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54842(MLS001123392 | SMR000627745 | cid_22553442)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by high content imaging beta-arrestin translocation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM75566(KSC-11-114-1 | KUC105392N | N-[2-[benzyl(tert-buty...)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of mu opioid receptor (unknown origin) using DAMGO by high content imaging beta-arrestin translocation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM54842(MLS001123392 | SMR000627745 | cid_22553442)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by DiscoveryRx b-arrestin PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 92 total ) | Next | Last >>
Jump to: