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Found 18 Enz. Inhib. hit(s) with all data for entry = 50006413
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataKi:  300nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50499815(CHEMBL3739883)
Affinity DataKi:  700nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50499816(CHEMBL3740596)
Affinity DataKi:  1.20E+3nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50239976(1314 TH | CHEBI:4885 | Ethionamide | Trecator | Tr...)
Affinity DataKi:  1.90E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50499814(Ektebin | Peteha | Prothionamide | Protionamide | ...)
Affinity DataKi:  2.40E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50499813(CHEMBL3741839)
Affinity DataKi:  2.70E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM60920(thionicotinamide)
Affinity DataKi:  4.30E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50499817(CHEMBL2441351)
Affinity DataKi:  2.23E+4nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50499815(CHEMBL3739883)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50239976(1314 TH | CHEBI:4885 | Ethionamide | Trecator | Tr...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50499816(CHEMBL3740596)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50499814(Ektebin | Peteha | Prothionamide | Protionamide | ...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM60920(thionicotinamide)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50499813(CHEMBL3741839)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50499817(CHEMBL2441351)
Affinity DataIC50:  4.38E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50240030(Acetanilide | Antifebrin | CHEBI:28884)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50336507(4-pyridinecarbohydrazide(Isoniazid) | CHEMBL64 | D...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed