Report error Found 113 Enz. Inhib. hit(s) with all data for entry = 50047396
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 0.810nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at human D3 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 2.5nMAssay Description:Agonist activity at human D2 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 3.30nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 3.70nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 4.60nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHO cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]th...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Agonist activity at human D2 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 7.60nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 7.70nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 8.20nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 14nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Agonist activity at human D2 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 18nMAssay Description:Agonist activity at human D3 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 18nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at human D3 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 23nMAssay Description:Agonist activity at human D2 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 26nMAssay Description:Agonist activity at human D3 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 28nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 29nMAssay Description:Agonist activity at human D2 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair







3D Structure (crystal)





