BindingDB PrimarySearch

Found 63 Enz. Inhib. hit(s) with all data for entry = 50009741

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)

IC50: 1.40nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase CHEMBL DrugBank MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531784(Fanotaprim | TRC-2533 | TRC-2533-NX | US11530198, ...)

IC50: 1.60nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531801(CHEMBL4461133)

IC50: 2.70nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531789(CHEMBL4582435)

IC50: 3.90nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531785(CHEMBL4543226 | US11530198, Example 69)

IC50: 4nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)

IC50: 4.10nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase CHEMBL DrugBank MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531777(CHEMBL4591654)

IC50: 4.30nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM66082((2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methy...)

IC50: 4.70nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase DrugBank MCE
KEGG PC cid PC sid PDB Similars

Details Article PubMed DrugBank
PDB

3D Structure (crystal)

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531786(CHEMBL4573445 | US11530198, Example 74)

IC50: 4.80nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531780(CHEMBL4464707 | US11530198, Example 73)

IC50: 6nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50203246(CHEMBL3953119 | US11530198, Example 2)

IC50: 8.80nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531781(CHEMBL4459877)

IC50: 9.20nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531797(CHEMBL4550110 | US11530198, Example 86)

IC50: 9.90nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531798(CHEMBL4466302 | US11530198, Example 104)

IC50: 10nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531788(CHEMBL4519642)

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531790(CHEMBL4439025)

IC50: 13nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531787(CHEMBL4584470 | US11530198, Example 103)

IC50: 27nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531799(CHEMBL4435247 | US11530198, Example 66)

IC50: 29nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531796(CHEMBL4544467 | US11530198, Example 12)

IC50: 31nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531795(CHEMBL4552468)

IC50: 32nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531783(CHEMBL4591892 | US11530198, Example 87)

IC50: 33nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531792(CHEMBL4544894)

IC50: 40nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531791(CHEMBL4456834 | US11530198, Example 6)

IC50: 46nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531778(CHEMBL4546142 | US11530198, Example 9)

IC50: 58nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531800(CHEMBL4535103 | US11530198, Example 3)

IC50: 62nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531794(CHEMBL4549054 | US11530198, Example 7)

IC50: 75nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM66082((2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methy...)

IC50: 78nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase DrugBank MCE
KEGG PC cid PC sid PDB Similars

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)

IC50: 139nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531793(CHEMBL4525462 | US11530198, Example 8)

IC50: 181nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531789(CHEMBL4582435)

IC50: 200nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531779(CHEMBL4553229 | US11530198, Example 4)

IC50: 209nMAssay Description:Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531781(CHEMBL4459877)

IC50: 237nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531801(CHEMBL4461133)

IC50: 300nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531784(Fanotaprim | TRC-2533 | TRC-2533-NX | US11530198, ...)

IC50: 308nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase PC cid PC sid PDB

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531795(CHEMBL4552468)

IC50: 347nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531777(CHEMBL4591654)

IC50: 468nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531800(CHEMBL4535103 | US11530198, Example 3)

IC50: 541nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50203246(CHEMBL3953119 | US11530198, Example 2)

IC50: 689nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)

IC50: 760nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531790(CHEMBL4439025)

IC50: 819nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531785(CHEMBL4543226 | US11530198, Example 69)

IC50: 935nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531797(CHEMBL4550110 | US11530198, Example 86)

IC50: 973nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531791(CHEMBL4456834 | US11530198, Example 6)

IC50: 1.09E+3nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531780(CHEMBL4464707 | US11530198, Example 73)

IC50: 1.10E+3nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531787(CHEMBL4584470 | US11530198, Example 103)

IC50: 1.30E+3nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531798(CHEMBL4466302 | US11530198, Example 104)

IC50: 1.33E+3nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531788(CHEMBL4519642)

IC50: 1.36E+3nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531786(CHEMBL4573445 | US11530198, Example 74)

IC50: 1.43E+3nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531792(CHEMBL4544894)

IC50: 1.54E+3nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Dihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

Curated by ChEMBL

BDBM50531799(CHEMBL4435247 | US11530198, Example 66)

IC50: 1.63E+3nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Displayed 1 to 50 (of 63 total ) | Next | Last >>