Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50010638
TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540803(CHEMBL4633299)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC6 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC6 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC6 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540803(CHEMBL4633299)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant HDAC8 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant HDAC8 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant HDAC1 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 3(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant HDAC3 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant HDAC5 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540803(CHEMBL4633299)
Affinity DataIC50: 430nMAssay Description:Inhibition of human recombinant HDAC1 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540803(CHEMBL4633299)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant HDAC3 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant HDAC4 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant HDAC1 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 920nMAssay Description:Inhibition of human recombinant HDAC2 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540803(CHEMBL4633299)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of human recombinant HDAC2 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of human recombinant HDAC3 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human recombinant HDAC8 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of human recombinant HDAC2 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540805(CHEMBL4641719)
Affinity DataIC50: 5.78E+3nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540803(CHEMBL4633299)
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM259332(US9505745, 9 | US9790212, Example 9)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540803(CHEMBL4633299)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of human recombinant HDAC5 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540806(CHEMBL4639520)
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540803(CHEMBL4633299)
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of human recombinant HDAC4 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540804(CHEMBL4639495)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human recombinant HDAC5 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed