Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50028743
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258790BDBM50258790((S)-2-amino-N-(3-(5-(5-(benzo[d]thiazol-7-yl)-1,3,...)
Affinity DataIC50: 40nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258787BDBM50258787((S)-2-amino-N-(3-(5-(5-(2-methoxyphenyl)-1,3,4-oxa...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258814BDBM50258814((S)-2-amino-N-(3-(5-(5-(2-methoxyphenylamino)-1,3,...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258789BDBM50258789((S)-2-amino-N-(3-(5-(5-(2-chlorophenyl)-1,3,4-oxad...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258747BDBM50258747((S)-2-amino-N-(3-(5-(5-phenyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27659BDBM27659(CHEMBL466658 | 1-(3-{[(2S)-2-aminopropanamido]meth...)
Affinity DataIC50: 80nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258815BDBM50258815((S)-2-amino-N-(3-(3-methyl-5-(5-phenyl-1,3,4-oxadi...)
Affinity DataIC50: 130nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258788BDBM50258788((S)-2-amino-N-(3-(5-(5-(3-methoxyphenyl)-1,3,4-oxa...)
Affinity DataIC50: 160nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258748BDBM50258748((S)-2-amino-N-(3-(5-(3-phenyl-1,2,4-oxadiazol-5-yl...)
Affinity DataIC50: 210nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258749BDBM50258749((S)-2-amino-N-(3-(5-(5-benzyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 310nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258859BDBM50258859((S)-2-amino-N-(3-(4-(5-phenyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 360nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258817BDBM50258817((S)-2-amino-N-(3-(1-methyl-4-(5-phenyl-1,3,4-oxadi...)
Affinity DataIC50: 400nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258750BDBM50258750((S)-2-amino-N-(3-(5-(5-(pyridin-4-yl)-1,3,4-oxadia...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258860BDBM50258860((S)-2-amino-N-(3-(5-(5-phenyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258816BDBM50258816((S)-2-amino-N-(3-(1-methyl-4-(5-phenyl-1,3,4-oxadi...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258862BDBM50258862((S)-N1-(3-(5-(5-phenyl-1,3,4-oxadiazol-2-yl)-3-(tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258861BDBM50258861((S)-2-amino-N-methyl-N-(3-(5-(5-phenyl-1,3,4-oxadi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258790BDBM50258790((S)-2-amino-N-(3-(5-(5-(benzo[d]thiazol-7-yl)-1,3,...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PRMT1 by methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258790BDBM50258790((S)-2-amino-N-(3-(5-(5-(benzo[d]thiazol-7-yl)-1,3,...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PRMT3 by methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258790BDBM50258790((S)-2-amino-N-(3-(5-(5-(benzo[d]thiazol-7-yl)-1,3,...)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258790BDBM50258790((S)-2-amino-N-(3-(5-(5-(benzo[d]thiazol-7-yl)-1,3,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 expressed in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258790BDBM50258790((S)-2-amino-N-(3-(5-(5-(benzo[d]thiazol-7-yl)-1,3,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 expressed in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258790BDBM50258790((S)-2-amino-N-(3-(5-(5-(benzo[d]thiazol-7-yl)-1,3,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 expressed in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258790BDBM50258790((S)-2-amino-N-(3-(5-(5-(benzo[d]thiazol-7-yl)-1,3,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19 expressed in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed