Compile Data Set for Download or QSAR
Report error Found 94 Enz. Inhib. hit(s) with all data for entry = 2148
LigandChemical structure of BindingDB Monomer ID 17428BDBM17428(N-[5-(benzylsulfanyl)-4H-1,2,4-triazol-3-yl]pyridi...)
Affinity DataKi:  0.0400nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17355BDBM17355(5-(benzylsulfanyl)-N-(2-methylphenyl)-4H-1,2,4-tri...)
Affinity DataKi:  0.0400nM ΔG°:  -58.8kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17388BDBM17388(5-(benzylsulfanyl)-N-(4-methoxyphenyl)-4H-1,2,4-tr...)
Affinity DataKi:  0.0500nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17365BDBM17365(5-(benzylsulfanyl)-N-(4-methylphenyl)-4H-1,2,4-tri...)
Affinity DataKi:  0.0700nM ΔG°:  -57.4kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17390BDBM17390(5-{[(2-fluorophenyl)methyl]sulfanyl}-N-(4-methoxyp...)
Affinity DataKi:  0.130nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17362BDBM17362(5-[(3-methylbut-2-en-1-yl)sulfanyl]-N-(2-methylphe...)
Affinity DataKi:  0.150nM ΔG°:  -55.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17395BDBM17395(N-(4-methoxyphenyl)-5-[(3-methylbut-2-en-1-yl)sulf...)
Affinity DataKi:  0.160nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17358BDBM17358(5-{[(2-fluorophenyl)methyl]sulfanyl}-N-(2-methylph...)
Affinity DataKi:  0.230nM ΔG°:  -54.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17430BDBM17430(N-(5-{[(2-fluorophenyl)methyl]sulfanyl}-4H-1,2,4-t...)
Affinity DataKi:  0.300nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17411BDBM17411(methyl 4-[(5-{[(2-fluorophenyl)methyl]sulfanyl}-4H...)
Affinity DataKi:  0.410nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17377BDBM17377(5-(benzylsulfanyl)-N-(4-chlorophenyl)-4H-1,2,4-tri...)
Affinity DataKi:  0.430nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17431BDBM17431(N-(5-{[(3,4-difluorophenyl)methyl]sulfanyl}-4H-1,2...)
Affinity DataKi:  0.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17416BDBM17416(methyl 4-({5-[(3-methylbut-2-en-1-yl)sulfanyl]-4H-...)
Affinity DataKi:  0.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17352BDBM17352(5-(benzylsulfanyl)-N-phenyl-4H-1,2,4-triazol-3-ami...)
Affinity DataKi:  0.5nM ΔG°:  -52.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17385BDBM17385(N-(4-chlorophenyl)-5-[(3-methylbut-2-en-1-yl)sulfa...)
Affinity DataKi:  0.520nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17380BDBM17380(N-(4-chlorophenyl)-5-{[(2-fluorophenyl)methyl]sulf...)
Affinity DataKi:  0.610nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17368BDBM17368(5-{[(2-fluorophenyl)methyl]sulfanyl}-N-(4-methylph...)
Affinity DataKi:  0.650nM ΔG°:  -51.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17408BDBM17408(methyl 4-{[5-(benzylsulfanyl)-4H-1,2,4-triazol-3-y...)
Affinity DataKi:  0.700nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17354BDBM17354(N-phenyl-5-[(thiophen-2-ylmethyl)sulfanyl]-4H-1,2,...)
Affinity DataKi:  0.75nM ΔG°:  -51.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17418BDBM17418(methyl 4-[(5-{[(5-methyl-1,2-oxazol-3-yl)methyl]su...)
Affinity DataKi:  0.800nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17413BDBM17413(methyl 4-({5-[(pyridin-2-ylmethyl)sulfanyl]-4H-1,2...)
Affinity DataKi:  0.900nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17414BDBM17414(methyl 4-({5-[(pyridin-4-ylmethyl)sulfanyl]-4H-1,2...)
Affinity DataKi:  0.900nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17405BDBM17405(N-(3,4-dimethoxyphenyl)-5-[(3-methylbut-2-en-1-yl)...)
Affinity DataKi:  0.900nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17442BDBM17442(5-[(3-methylbut-2-en-1-yl)sulfanyl]-N-phenyl-4H-1,...)
Affinity DataKi:  1nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17446BDBM17446((3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-m...)
Affinity DataKi:  1nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17373BDBM17373(5-[(3-methylbut-2-en-1-yl)sulfanyl]-N-(4-methylphe...)
Affinity DataKi:  1.20nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17412BDBM17412(methyl 4-[(5-{[(3,4-difluorophenyl)methyl]sulfanyl...)
Affinity DataKi:  1.30nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17400BDBM17400(N-(3,4-dimethoxyphenyl)-5-{[(2-fluorophenyl)methyl...)
Affinity DataKi:  1.30nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17381BDBM17381(N-(4-chlorophenyl)-5-{[(3,4-difluorophenyl)methyl]...)
Affinity DataKi:  1.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17436BDBM17436(N-(5-{[(5-methyl-1,2-oxazol-3-yl)methyl]sulfanyl}-...)
Affinity DataKi:  1.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17396BDBM17396(N-(4-methoxyphenyl)-5-{[(5-methyl-1,2-oxazol-3-yl)...)
Affinity DataKi:  1.60nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17397BDBM17397(5-(benzylsulfanyl)-N-(3,4-dimethoxyphenyl)-4H-1,2,...)
Affinity DataKi:  1.70nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17429BDBM17429(N-(5-{[(2-methylphenyl)methyl]sulfanyl}-4H-1,2,4-t...)
Affinity DataKi:  1.70nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17387BDBM17387(N-(4-chlorophenyl)-5-{[(5-methyl-1,2-oxazol-3-yl)m...)
Affinity DataKi:  1.80nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17443BDBM17443(1,2,4-Triazole Compound, 102 | N-[2-(propan-2-yl)p...)
Affinity DataKi:  2nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17391BDBM17391(5-{[(3,4-difluorophenyl)methyl]sulfanyl}-N-(4-meth...)
Affinity DataKi:  2.10nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17359BDBM17359(5-{[(3,4-difluorophenyl)methyl]sulfanyl}-N-(2-meth...)
Affinity DataKi:  2.40nM ΔG°:  -48.7kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17383BDBM17383(N-(4-chlorophenyl)-5-[(pyridin-4-ylmethyl)sulfanyl...)
Affinity DataKi:  2.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17356BDBM17356(N-(2-methylphenyl)-5-{[(2-methylphenyl)methyl]sulf...)
Affinity DataKi:  2.5nM ΔG°:  -48.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17415BDBM17415(methyl 4-({5-[(cyclohexylmethyl)sulfanyl]-4H-1,2,4...)
Affinity DataKi:  2.70nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17444BDBM17444(5-[(furan-2-ylmethyl)sulfanyl]-N-[2-(propan-2-yl)p...)
Affinity DataKi:  3nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17433BDBM17433(N-{5-[(pyridin-4-ylmethyl)sulfanyl]-4H-1,2,4-triaz...)
Affinity DataKi:  3nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17394BDBM17394(5-[(cyclohexylmethyl)sulfanyl]-N-(4-methoxyphenyl)...)
Affinity DataKi:  3.10nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17361BDBM17361(5-[(cyclohexylmethyl)sulfanyl]-N-(2-methylphenyl)-...)
Affinity DataKi:  3.30nM ΔG°:  -47.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17369BDBM17369(5-{[(3,4-difluorophenyl)methyl]sulfanyl}-N-(4-meth...)
Affinity DataKi:  3.30nM ΔG°:  -47.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17375BDBM17375(5-{[(5-methyl-1,2-oxazol-3-yl)methyl]sulfanyl}-N-(...)
Affinity DataKi:  3.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17364BDBM17364(5-{[(5-methyl-1,2-oxazol-3-yl)methyl]sulfanyl}-N-(...)
Affinity DataKi:  3.60nM ΔG°:  -47.7kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17360BDBM17360(N-(2-methylphenyl)-5-[(pyridin-4-ylmethyl)sulfanyl...)
Affinity DataKi:  3.70nM ΔG°:  -47.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17363BDBM17363(5-{[(2-methyl-1,3-thiazol-4-yl)methyl]sulfanyl}-N-...)
Affinity DataKi:  3.80nM ΔG°:  -47.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17417BDBM17417(methyl 4-[(5-{[(2-methyl-1,3-thiazol-4-yl)methyl]s...)
Affinity DataKi:  3.80nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
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