Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50007343
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010594(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010594(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50:  6nMAssay Description:Inhibitory binding of [3H]-pirenzepine to human Muscarinic acetylcholine receptor M1 in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  7.5nMAssay Description:Inhibitory binding of [3H]-spiperone to Dopamine receptor D2 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061559(CHEMBL72292 | Trifluoro-methanesulfonic acid 11-(4...)
Affinity DataIC50:  8nMAssay Description:Inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  9.40nMAssay Description:Inhibitory binding of [3H]-pirenzepine to human Muscarinic acetylcholine receptor M1 in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010594(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50:  11nMAssay Description:Inhibitory binding of [3H]-SCH-23,390 to Dopamine receptor D1 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061558(2-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010594(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010594(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50:  13nMAssay Description:Inhibitory binding of [3H]-spiperone to Dopamine receptor D2 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061555(8-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[...)
Affinity DataIC50:  19nMAssay Description:Inhibitory binding of [3H]-pirenzepine to human Muscarinic acetylcholine receptor M1 in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061558(2-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[...)
Affinity DataIC50:  21nMAssay Description:Inhibition of [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  23nMAssay Description:Inhibitory binding of [3H]-mepyramine to histamine H1 receptors in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061557(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  27nMAssay Description:Inhibitory binding of [3H]-pirenzepine to human Muscarinic acetylcholine receptor M1 in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061559(CHEMBL72292 | Trifluoro-methanesulfonic acid 11-(4...)
Affinity DataIC50:  31nMAssay Description:Inhibitory binding of [3H]-spiperone to Dopamine receptor D2 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061559(CHEMBL72292 | Trifluoro-methanesulfonic acid 11-(4...)
Affinity DataIC50:  34nMAssay Description:Inhibition of [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061556(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  35nMAssay Description:Inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061560(CHEMBL310712 | Trifluoro-methanesulfonic acid 11-(...)
Affinity DataIC50:  35nMAssay Description:Inhibitory binding of [3H]-pirenzepine to human Muscarinic acetylcholine receptor M1 in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  36nMAssay Description:Inhibitory binding of [3H]-SCH-23,390 to Dopamine receptor D1 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061556(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  37nMAssay Description:Inhibitory binding of [3H]-pirenzepine to human Muscarinic acetylcholine receptor M1 in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061558(2-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[...)
Affinity DataIC50:  39nMAssay Description:Inhibitory binding of [3H]-pirenzepine to human Muscarinic acetylcholine receptor M1 in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061559(CHEMBL72292 | Trifluoro-methanesulfonic acid 11-(4...)
Affinity DataIC50:  47nMAssay Description:Inhibitory binding of [3H]-mepyramine to histamine H1 receptors in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  55nMAssay Description:Inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061559(CHEMBL72292 | Trifluoro-methanesulfonic acid 11-(4...)
Affinity DataIC50:  64nMAssay Description:Inhibitory binding of [3H]-SCH-23,390 to Dopamine receptor D1 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061558(2-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[...)
Affinity DataIC50:  68nMAssay Description:Inhibitory binding of [3H]-spiperone to Dopamine receptor D2 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061556(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  81nMAssay Description:Inhibition of [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061555(8-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[...)
Affinity DataIC50:  86nMAssay Description:Inhibition of [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  130nMAssay Description:Inhibitory binding of [3H]-SCH-23,390 to Dopamine receptor D1 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061555(8-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[...)
Affinity DataIC50:  160nMAssay Description:Inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061557(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  310nMAssay Description:Inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  330nMAssay Description:Inhibitory binding of [3H]-spiperone to Dopamine receptor D2 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061557(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  440nMAssay Description:Inhibition of [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061558(2-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[...)
Affinity DataIC50:  550nMAssay Description:Inhibitory binding of [3H]-SCH-23,390 to Dopamine receptor D1 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061556(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  550nMAssay Description:Inhibitory binding of [3H]-SCH-23,390 to Dopamine receptor D1 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061560(CHEMBL310712 | Trifluoro-methanesulfonic acid 11-(...)
Affinity DataIC50:  550nMAssay Description:Inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061560(CHEMBL310712 | Trifluoro-methanesulfonic acid 11-(...)
Affinity DataIC50:  620nMAssay Description:Inhibition of [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061560(CHEMBL310712 | Trifluoro-methanesulfonic acid 11-(...)
Affinity DataIC50:  720nMAssay Description:Inhibitory binding of [3H]-mepyramine to histamine H1 receptors in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061560(CHEMBL310712 | Trifluoro-methanesulfonic acid 11-(...)
Affinity DataIC50:  930nMAssay Description:Inhibitory binding of [3H]-SCH-23,390 to Dopamine receptor D1 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory binding of [3H]-mepyramine to histamine H1 receptors in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061559(CHEMBL72292 | Trifluoro-methanesulfonic acid 11-(4...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory binding of [3H]-pirenzepine to human Muscarinic acetylcholine receptor M1 in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061556(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory binding of [3H]-spiperone to Dopamine receptor D2 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061555(8-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibitory binding of [3H]-spiperone to Dopamine receptor D2 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibitory binding of [3H]-pirenzepine to human Muscarinic acetylcholine receptor M1 in membranes from CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061557(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibitory binding of [3H]-spiperone to Dopamine receptor D2 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061555(8-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibitory binding of [3H]-SCH-23,390 to Dopamine receptor D1 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061560(CHEMBL310712 | Trifluoro-methanesulfonic acid 11-(...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibitory binding of [3H]-spiperone to Dopamine receptor D2 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50061557(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibitory binding of [3H]-SCH-23,390 to Dopamine receptor D1 in membranes from rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed