Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50007953
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069575(3-Benzo[1,2,5]thiadiazol-5-yl-5-hydroxy-5-(4-metho...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50034267(3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methox...)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069569(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)
Affinity DataIC50:  22nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069571(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50:  33nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069573(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50:  97nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069565(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)
Affinity DataIC50:  150nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069566(3-(4-Methoxy-phenyl)-1-(6-methyl-benzo[1,2,5]thiad...)
Affinity DataIC50:  160nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069570(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-3-(4-methoxy-p...)
Affinity DataIC50:  210nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069567(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)
Affinity DataIC50:  250nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069572(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-4-(4-methoxy-p...)
Affinity DataIC50:  300nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50034267(3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methox...)
Affinity DataIC50:  300nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069566(3-(4-Methoxy-phenyl)-1-(6-methyl-benzo[1,2,5]thiad...)
Affinity DataIC50:  330nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069575(3-Benzo[1,2,5]thiadiazol-5-yl-5-hydroxy-5-(4-metho...)
Affinity DataIC50:  340nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069564(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)
Affinity DataIC50:  370nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069572(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-4-(4-methoxy-p...)
Affinity DataIC50:  390nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069568(1-Benzo[1,3]dioxol-5-ylmethyl-4-(4-methoxy-phenyl)...)
Affinity DataIC50:  440nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069565(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069570(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-3-(4-methoxy-p...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069568(1-Benzo[1,3]dioxol-5-ylmethyl-4-(4-methoxy-phenyl)...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069571(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069573(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069567(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50069574(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]oxadiazol-5-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069574(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]oxadiazol-5-...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069569(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50069564(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed