Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50007953
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069575BDBM50069575(3-Benzo[1,2,5]thiadiazol-5-yl-5-hydroxy-5-(4-metho...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50034267BDBM50034267(PD156707 | PD-156707 | CHEMBL8981 | 3-Benzo[1,3]di...)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069569BDBM50069569(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069571BDBM50069571(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50: 33nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069573BDBM50069573(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50: 97nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069565BDBM50069565(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069566BDBM50069566(3-(4-Methoxy-phenyl)-1-(6-methyl-benzo[1,2,5]thiad...)
Affinity DataIC50: 160nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069570BDBM50069570(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-3-(4-methoxy-p...)
Affinity DataIC50: 210nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069567BDBM50069567(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)
Affinity DataIC50: 250nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50034267BDBM50034267(PD156707 | PD-156707 | CHEMBL8981 | 3-Benzo[1,3]di...)
Affinity DataIC50: 300nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069572BDBM50069572(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-4-(4-methoxy-p...)
Affinity DataIC50: 300nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069566BDBM50069566(3-(4-Methoxy-phenyl)-1-(6-methyl-benzo[1,2,5]thiad...)
Affinity DataIC50: 330nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069575BDBM50069575(3-Benzo[1,2,5]thiadiazol-5-yl-5-hydroxy-5-(4-metho...)
Affinity DataIC50: 340nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069564BDBM50069564(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)
Affinity DataIC50: 370nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069572BDBM50069572(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-4-(4-methoxy-p...)
Affinity DataIC50: 390nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069568BDBM50069568(1-Benzo[1,3]dioxol-5-ylmethyl-4-(4-methoxy-phenyl)...)
Affinity DataIC50: 440nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069565BDBM50069565(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069570BDBM50069570(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-3-(4-methoxy-p...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069568BDBM50069568(1-Benzo[1,3]dioxol-5-ylmethyl-4-(4-methoxy-phenyl)...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069567BDBM50069567(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069573BDBM50069573(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069571BDBM50069571(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069574BDBM50069574(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]oxadiazol-5-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069574BDBM50069574(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]oxadiazol-5-...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069564BDBM50069564(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069569BDBM50069569(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed