Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50008303
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072289((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072283((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072286((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  2nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)
Affinity DataIC50:  4nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)
Affinity DataIC50:  6nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072290((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)
Affinity DataIC50:  7nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)
Affinity DataIC50:  10nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072287((3S,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahydro-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072289((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)
Affinity DataIC50:  21nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072290((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072287((3S,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahydro-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072282((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)
Affinity DataIC50:  37nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072293(5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  40nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072282((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)
Affinity DataIC50:  41nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072282((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)
Affinity DataIC50: >50nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)
Affinity DataIC50:  70nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)
Affinity DataIC50:  70nMAssay Description:Compound was evaluated for the inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072283((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  73nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072286((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  92nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072290((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)
Affinity DataIC50:  98nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)
Affinity DataIC50: >100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)
Affinity DataIC50: >100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072289((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)
Affinity DataIC50: >100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072283((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50: >100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072286((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50: >100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072293(5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  130nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072291(4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  220nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072288(3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for the inhibition of human leukocyte elastase(HLE).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072291(4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  1.68E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072291(4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  7.03E+4nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072288(3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072293(5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072288(3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed