Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 11690
TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640341BDBM640341(8-Amino-N-(cyclopropylmethyl)-5-(4- (1-(2-(dimethy...)
Affinity DataIC50: 0.880nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640350BDBM640350(2-(4-(4-(8-amino-3-(azetidine-1- carbonyl)-1,7-nap...)
Affinity DataIC50: 0.960nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640351BDBM640351(2-(4-(4-(8-amino-3-(azetidine-1- carbonyl)-1,7-nap...)
Affinity DataIC50: 1.01nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640354BDBM640354(8-amino-N-(2-methoxyethyl)-N- methyl-5-(4-(1-(2-(4...)
Affinity DataIC50: 1.07nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640345BDBM640345(8-amino-N-cyclopropyl-5-(4-(1-(2-(4- methylpiperaz...)
Affinity DataIC50: 1.10nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640346BDBM640346(8-amino-N-cyclopropyl-5-(4-(1-(2-(2- methoxyethyl)...)
Affinity DataIC50: 1.10nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640344BDBM640344(8-amino-N-cyclopropyl-5-(4-(1-(2- (dimethylamino)-...)
Affinity DataIC50: 1.11nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640353BDBM640353(8-amino-5-(4-(1-(2-(dimethylamino)- 2-oxoethyl)-1H...)
Affinity DataIC50: 1.24nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640352BDBM640352((8-amino-5-(4-(1-(2-methoxyethyl)- 1H-pyrazole-4-y...)
Affinity DataIC50: 1.27nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640342BDBM640342(8-amino-N-(cyclopropylmethyl)-5-(4- (1-(2-(4-methy...)
Affinity DataIC50: 1.40nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640349BDBM640349((8-amino-5-(4-(1-(2-methoxyethyl)- 1H-pyrazole-4-y...)
Affinity DataIC50: 1.44nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640343BDBM640343(8-amino-N-(cyclopropylmethyl)-5-(4- (1-(2-methoxye...)
Affinity DataIC50: 1.63nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640347BDBM640347(2-(4-(4-(8-amino-3-(4- methylpiperazine-1-carbonyl...)
Affinity DataIC50: 1.85nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640348BDBM640348(2-(4-(4-(8-amino-3-(4- methylpiperazine-1-carbonyl...)
Affinity DataIC50: 2.03nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandChemical structure of BindingDB Monomer ID 640355BDBM640355(8-amino-N-(2-methoxyethyl)-5-(4-(1- (2-methoxyethy...)
Affinity DataIC50: 2.27nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent