Compile Data Set for Download or QSAR
Report error Found 151 Enz. Inhib. hit(s) with all data for entry = 7826
TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221256(US9303015, 30c | US9303015, 30b | US9303015, 30a)
Affinity DataKd:  0.530nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221257(US9303015, 31c | US9303015, 31b | US9303015, 31a)
Affinity DataKd:  0.720nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221256(US9303015, 30c | US9303015, 30b | US9303015, 30a)
Affinity DataKd:  1.80nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221289(US9303015, 22c | US9303015, 22b)
Affinity DataKd:  2.90nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221258(US9303015, 32c | US9303015, 32b | US9303015, 32a)
Affinity DataKd:  3.30nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221236(US9303015, 10c | US9303015, 10b | US9303015, 10a)
Affinity DataKd:  3.40nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221257(US9303015, 31c | US9303015, 31b | US9303015, 31a)
Affinity DataKd:  3.60nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221243(US9303015, 17)
Affinity DataKd:  4.10nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221250(US9303015, 24)
Affinity DataKd:  4.20nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221246(US9303015, 20)
Affinity DataKd:  5.70nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221258(US9303015, 32c | US9303015, 32b | US9303015, 32a)
Affinity DataKd:  6.90nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221234(US9303015, 8)
Affinity DataKd:  7.20nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221235(US9303015, 9c | US9303015, 9b | US9303015, 9a)
Affinity DataKd:  8nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221232(US9303015, 6c | US9303015, 6b | US9303015, 6a)
Affinity DataKd:  8.30nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221236(US9303015, 10c | US9303015, 10b | US9303015, 10a)
Affinity DataKd:  8.5nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221256(US9303015, 30c | US9303015, 30b | US9303015, 30a)
Affinity DataKd:  8.90nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518,Y502F](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221253(US9303015, 27c | US9303015, 27b | US9303015, 27a)
Affinity DataIC50: 10nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221240(US9303015, 14c | US9303015, 14b | US9303015, 14a)
Affinity DataKd:  10nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221231(US9303015, 5c | US9303015, 5b | US9303015, 5a)
Affinity DataKd:  12nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221231(US9303015, 5c | US9303015, 5b | US9303015, 5a)
Affinity DataKd:  12nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221257(US9303015, 31c | US9303015, 31b | US9303015, 31a)
Affinity DataKd:  14nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221230(US9303015, 4)
Affinity DataKd:  14nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221253(US9303015, 27c | US9303015, 27b | US9303015, 27a)
Affinity DataKd:  14nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518,Y502F](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221234(US9303015, 8)
Affinity DataIC50: 16nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221229(US9303015, 3c | US9303015, 3b | US9303015, 3a)
Affinity DataKd:  17nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518,Y502F](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221257(US9303015, 31c | US9303015, 31b | US9303015, 31a)
Affinity DataIC50: 18nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221260(US9303015, 34)
Affinity DataKd:  18nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221251(US9303015, 25c | US9303015, 25b | US9303015, 25a)
Affinity DataKd:  20nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221240(US9303015, 14c | US9303015, 14b | US9303015, 14a)
Affinity DataKd:  22nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221261(US9303015, 35)
Affinity DataKd:  23nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221249(US9303015, 23)
Affinity DataKd:  26nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221231(US9303015, 5c | US9303015, 5b | US9303015, 5a)
Affinity DataKd:  26nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518,Y502F](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221231(US9303015, 5c | US9303015, 5b | US9303015, 5a)
Affinity DataIC50: 28nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518,Y502F](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221256(US9303015, 30c | US9303015, 30b | US9303015, 30a)
Affinity DataIC50: 31nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221242(US9303015, 16)
Affinity DataKd:  31nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221258(US9303015, 32c | US9303015, 32b | US9303015, 32a)
Affinity DataKd:  32nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221245(US9303015, 19)
Affinity DataKd:  32nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221262(US9303015, 36)
Affinity DataKd:  32nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221235(US9303015, 9c | US9303015, 9b | US9303015, 9a)
Affinity DataKd:  33nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221241(US9303015, 15b | US9303015, 15c | US9303015, 15a)
Affinity DataKd:  33nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221233(US9303015, 7)
Affinity DataKd:  34nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221240(US9303015, 14c | US9303015, 14b | US9303015, 14a)
Affinity DataKd:  34nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221264(US9303015, 38)
Affinity DataKd:  35nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221268(US9303015, 42)
Affinity DataKd:  37nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221236(US9303015, 10c | US9303015, 10b | US9303015, 10a)
Affinity DataKd:  39nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518,Y502F](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221231(US9303015, 5c | US9303015, 5b | US9303015, 5a)
Affinity DataIC50: 39nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221228(US9303015, 2c | US9303015, 2b | US9303015, 2a)
Affinity DataKd:  41nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221232(US9303015, 6c | US9303015, 6b | US9303015, 6a)
Affinity DataKd:  51nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518,Y502F](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221256(US9303015, 30c | US9303015, 30b | US9303015, 30a)
Affinity DataIC50: 58nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [258-518](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221229(US9303015, 3c | US9303015, 3b | US9303015, 3a)
Affinity DataKd:  59nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

Displayed 1 to 50 (of 151 total ) | Next | Last >>
Jump to: