Compile Data Set for Download or QSAR
Report error Found 266 for UniProtKB: Q15370
LigandPNGBDBM536223(US11242344, Example 129.4 | (2R)-1-((2S,4R)-4-hydr...)
Affinity DataKd:  29.3nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536223(US11242344, Example 129.4 | (2R)-1-((2S,4R)-4-hydr...)
Affinity DataKd:  43.8nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560814(US11389438, # 54)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560701(US11389438, # 11)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560818(US11389438, # 58)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560712(US11389438, # 44)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560809(US11389438, # 45)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560711(US11389438, # 43)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560812(US11389438, # 48)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560810(US11389438, # 46)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

LigandPNGBDBM536252(BDBM536273 | (2S)-1-((2S,4R)-2-(5-(4-Bromophenyl)-...)
Affinity DataIC50: 62.8nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560816(US11389438, # 56)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560702(US11389438, # 20)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560817(US11389438, # 57)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560703(US11389438, # 21)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560700(US11389438, # 3)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560815(US11389438, # 55)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560709(US11389438, # 25)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560698(US11389438, # 1)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560699(US11389438, # 2)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560813(US11389438, # 53)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560811(US11389438, # 47)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

LigandPNGBDBM536284(US11242344, Example 118.3 | US11242344, Example 11...)
Affinity DataKd:  128nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536198(US11242344, Example 104.4)
Affinity DataKd:  171nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536223(US11242344, Example 129.4 | (2R)-1-((2S,4R)-4-hydr...)
Affinity DataIC50: 202nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560707(US11389438, # 24)
Affinity DataKd:  300nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560705(US11389438, # 22)
Affinity DataKd:  300nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560706(US11389438, # 23)
Affinity DataKd:  300nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

LigandPNGBDBM536228(US11242344, Example 108.3)
Affinity DataKd: >300nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandPNGBDBM560710(US11389438, # 26)
Affinity DataKd:  300nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

LigandPNGBDBM536230(US11242344, Example 108.4)
Affinity DataKd: >300nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536223(US11242344, Example 129.4 | (2R)-1-((2S,4R)-4-hydr...)
Affinity DataIC50: 418nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536284(US11242344, Example 118.3 | US11242344, Example 11...)
Affinity DataIC50: 418nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536198(US11242344, Example 104.4)
Affinity DataIC50: 422nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536276(US11242344, Example 117.4 | US11242344, Example 11...)
Affinity DataKd:  625nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536277(US11242344, Example 1001.3 | US11242344, Example 1...)
Affinity DataIC50: 795nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM50099062(CHEMBL3344081 | US10730870, Example 3 | US11512083...)
Affinity DataIC50: 800nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50459896(CHEMBL4226250)
Affinity DataIC50: 800nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM536210(US11242344, Example 106.4 | US11242344, Example 10...)
Affinity DataKd:  895nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536190(US11242344, Example 103.4)
Affinity DataKd:  1.09E+3nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536206(US11242344, Example 105.4)
Affinity DataKd:  1.58E+3nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536276(US11242344, Example 117.4 | US11242344, Example 11...)
Affinity DataIC50: 1.62E+3nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536240(1-Cyano-N-((2S)-1-((4R)-4-hydroxy-2-((S)-5-methyl-...)
Affinity DataKd:  1.86E+3nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536178(N-((2S)-1-((4R)-4-Hydroxy-2-(5-methyl-5-(4-(4-meth...)
Affinity DataKd:  1.96E+3nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536254(US11242344, Example 113.4)
Affinity DataIC50: 2.28E+3nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536250((2R)-1-((2S,4R)-2-(5-(4-Bromophenyl)-5-methyl-4,5-...)
Affinity DataKd:  2.49E+3nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536210(US11242344, Example 106.4 | US11242344, Example 10...)
Affinity DataIC50: 2.96E+3nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536254(US11242344, Example 113.4)
Affinity DataKd:  3.17E+3nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536226(US11242344, Example 108.2)
Affinity DataKd:  3.95E+3nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandPNGBDBM536183(US11242344, Example 123.2 | 2-((2S)-1-((4R)-4-hydr...)
Affinity DataKd:  3.98E+3nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

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