Compile Data Set for Download or QSAR
maximum 50k data
Found 200 of affinity data for UniProtKB/TrEMBL: O95718
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312140(6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(4-methoxyphen...)
Affinity DataKi:  0.480nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312151((E)-6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(prop-1-en...)
Affinity DataKi:  1.66nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312096(4-bromo-6,8-dihydroxy-2-(4-hydroxyphenyl)isoquinol...)
Affinity DataKi:  3nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312133(US9604931, 12z)
Affinity DataKi:  3nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312149(6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(4-methoxyphen...)
Affinity DataKi:  3.03nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312139(2-(3-fluoro-4-hydroxyphenyl)-6,8-dihydroxy-4-vinyl...)
Affinity DataKi:  3.96nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312134(4-bromo-6-methoxy-2-(4-methoxyphenyl)-1-oxo-1,2-di...)
Affinity DataKi:  6nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312135(6,8-dihydroxy-2-(4-hydroxyphenyl)-1-oxo-1,2-dihydr...)
Affinity DataKi:  7nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312136(4-bromo-6-hydroxy-2-(4-hydroxyphenyl)-1-oxo-1,2-di...)
Affinity DataKi:  46nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM310198(4-bromo-6-hydroxy-2-(4-hydroxyphenyl)isoquinolin-1...)
Affinity DataKi:  49nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312137(6-hydroxy-2-(4-hydroxyphenyl)-4-phenylisoquinolin-...)
Affinity DataKi:  130nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312138(6-hydroxy-2-(4-hydroxyphenol)-4-(4-methoxyphenyl)i...)
Affinity DataKi:  252nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  8.70nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233271(CHEMBL4071073)
Affinity DataIC50:  10nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50427842(CHEMBL2326072)
Affinity DataIC50:  19nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50427834(CHEMBL2326068)
Affinity DataIC50:  41nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233269(CHEMBL4100590)
Affinity DataIC50:  50nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212173(7-bromo-6H-chromeno[4,3-b]quinoline-3,9-diol | CHE...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM544469(87 | US11285226, Compound 27a)
Affinity DataIC50:  70nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485072(US10934303, Cmpd No. 27a | US10934303, Example 87)
Affinity DataIC50:  70nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212166(7-chloro-6H-chromeno[4,3-b]quinoline-3,9-diol | CH...)
Affinity DataIC50:  88nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212172(3,9-dihydroxy-6H-chromeno[4,3-b]quinoline-7-carbon...)
Affinity DataIC50:  98nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50427836(CHEMBL2326070)
Affinity DataIC50:  112nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50427841(CHEMBL2326073)
Affinity DataIC50:  121nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50427835(CHEMBL2326069)
Affinity DataIC50:  151nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50427838(CHEMBL2326076)
Affinity DataIC50:  185nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233266(CHEMBL4092854)
Affinity DataIC50:  210nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171724(4-Bromo-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-bro...)
Affinity DataIC50:  212nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171726(4-Chloro-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-ch...)
Affinity DataIC50:  213nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233264(CHEMBL4085105)
Affinity DataIC50:  300nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50427840(CHEMBL2326074)
Affinity DataIC50:  331nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233267(CHEMBL4084142)
Affinity DataIC50:  350nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  395nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50427839(CHEMBL2326075)
Affinity DataIC50:  436nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171712(6-Hydroxy-2-(4-hydroxy-phenyl)-quinoline-4-carboni...)
Affinity DataIC50:  455nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212165(7-(3-chlorophenyl)-6H-chromeno[4,3-b]quinoline-3,9...)
Affinity DataIC50:  504nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171727(2-(4-Hydroxy-phenyl)-4-vinyl-quinolin-6-ol | 2-(4-...)
Affinity DataIC50:  504nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212161(7-vinyl-6H-chromeno[4,3-b]quinoline-3,9-diol | CHE...)
Affinity DataIC50:  526nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212163(7-(4-methoxyphenyl)-6H-chromeno[4,3-b]quinoline-3,...)
Affinity DataIC50:  549nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233273(CHEMBL4064664)
Affinity DataIC50:  550nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50427837(CHEMBL2326071)
Affinity DataIC50:  566nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233265(CHEMBL4065193)
Affinity DataIC50:  600nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212170(7-ethynyl-6H-chromeno[4,3-b]quinoline-3,9-diol | C...)
Affinity DataIC50:  624nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171723(4-Ethyl-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-eth...)
Affinity DataIC50:  634nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212162(7-ethyl-6H-chromeno[4,3-b]quinoline-3,9-diol | CHE...)
Affinity DataIC50:  641nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Affinity DataIC50:  650nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50193253(CHEMBL3961676)
Affinity DataIC50:  722nMAssay Description:Inhibition of fluorescien-conjugated coactivator PGC1a binding to ERRbeta (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233268(CHEMBL4073790)
Affinity DataIC50:  750nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50555949(CHEMBL4795846)
Affinity DataIC50:  774nMAssay Description:Binding affinity to ERRbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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