Affinity DataKi: 0.480nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 1.66nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 3.03nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 3.96nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 252nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 121nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 151nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 185nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 212nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 213nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 331nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 395nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 436nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 455nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 504nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 504nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 526nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 549nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 566nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 624nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 634nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 641nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
Affinity DataIC50: 722nMAssay Description:Inhibition of fluorescien-conjugated coactivator PGC1a binding to ERRbeta (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
Affinity DataIC50: 774nMAssay Description:Binding affinity to ERRbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair