Compile Data Set for Download or QSAR
Report error Found 131 of affinity data for UniProtKB/TrEMBL: P22443
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014315BDBM50014315((rac)-6-((4-chlorophenyl)(1H-1,2,4-triazol-1-yl)me...)
Affinity DataIC50: 3nMAssay Description:Binding affinity for Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014777BDBM50014777(CHEMBL135381 | 1-Di-p-tolylmethyl-1H-imidazole)
Affinity DataEC50:  6.40nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014754BDBM50014754(CHEMBL135063 | 1-[(4-Chloro-phenyl)-(4-methoxy-phe...)
Affinity DataEC50:  8.40nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014780BDBM50014780(CHEMBL341386 | 1-[Bis-(4-chloro-phenyl)-methyl]-1H...)
Affinity DataEC50:  8.80nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014773BDBM50014773(CHEMBL436369 | 1-[Bis-(4-bromo-phenyl)-methyl]-1H-...)
Affinity DataEC50:  8.90nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014803BDBM50014803(CHEMBL135563 | 4-[Bis-(4-chloro-phenyl)-methyl]-4H...)
Affinity DataEC50:  9.30nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014776BDBM50014776(CHEMBL137604 | 1-[bis(4-chlorophenyl)(1H-imidazol-...)
Affinity DataEC50:  9.40nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014771BDBM50014771(CHEMBL137552 | Bis-(4-chloro-phenyl)-thiazol-5-yl-...)
Affinity DataEC50:  9.60nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014764BDBM50014764(CHEMBL135172 | 5-[Bis-(4-chloro-phenyl)-imidazol-1...)
Affinity DataEC50:  11nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014809BDBM50014809(CHEMBL135595 | 1-[(4-Chloro-phenyl)-(4-trifluorome...)
Affinity DataEC50:  11nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014796BDBM50014796(CHEMBL335050 | 1-[(4-Methoxy-phenyl)-p-tolyl-methy...)
Affinity DataEC50:  11nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014763BDBM50014763(CHEMBL137001 | 4-[Bis-(4-chloro-phenyl)-imidazol-1...)
Affinity DataEC50:  11nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014755BDBM50014755(CHEMBL135494 | 1-[Bis-(4-methoxy-phenyl)-methyl]-1...)
Affinity DataEC50:  13nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014800BDBM50014800(CHEMBL344904 | 1-[bis(4-chlorophenyl)(1H-imidazol-...)
Affinity DataEC50:  16nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014759BDBM50014759(CHEMBL133262 | 5-[Bis-(4-chloro-phenyl)-imidazol-1...)
Affinity DataEC50:  17nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136199BDBM50136199(CHEMBL3349548)
Affinity DataKi:  18nMAssay Description:Inhibition of aromatase in rat mammary tumorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014814BDBM50014814(CHEMBL135378 | 4-[Bis-(4-chloro-phenyl)-imidazol-1...)
Affinity DataEC50:  18nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014782BDBM50014782(CHEMBL132929 | 1-[Bis-(4-chloro-phenyl)-methyl]-1H...)
Affinity DataEC50:  19nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014804BDBM50014804(CHEMBL132708 | Bis-(4-chloro-phenyl)-isothiazol-5-...)
Affinity DataEC50:  19nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014808BDBM50014808(CHEMBL343072 | 1-[(4-Chloro-phenyl)-phenyl-methyl]...)
Affinity DataEC50:  20nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014320BDBM50014320(LY-113174 | CHEMBL101324 | 8-Chloro-5-(4-chloro-ph...)
Affinity DataKi:  24nMAssay Description:Binding affinity for Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014775BDBM50014775(CHEMBL342180 | 5-[Bis-(4-chloro-phenyl)-imidazol-1...)
Affinity DataEC50:  26nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014785BDBM50014785(CHEMBL135921 | Bis-(4-chloro-phenyl)-(1H-imidazol-...)
Affinity DataEC50:  28nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014324BDBM50014324(CHEMBL29669 | 5-[Bis-(4-chloro-phenyl)-methyl]-pyr...)
Affinity DataKi:  29nMAssay Description:Binding affinity for Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014783BDBM50014783(CHEMBL133198 | 2-[Bis-(4-chloro-phenyl)-imidazol-1...)
Affinity DataEC50:  29nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014778BDBM50014778(CHEMBL137589 | Bis-(4-chloro-phenyl)-(1H-pyrazol-4...)
Affinity DataEC50:  30nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014797BDBM50014797(CHEMBL137373 | 1-[Bis-(4-fluoro-phenyl)-methyl]-1H...)
Affinity DataEC50:  40nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014810BDBM50014810(CHEMBL135606 | 1-[Bis-(4-nitro-phenyl)-methyl]-1H-...)
Affinity DataEC50:  40nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014756BDBM50014756(CHEMBL335215 | 1-[Bis-(4-chloro-phenyl)-methyl]-1H...)
Affinity DataEC50:  42nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367548BDBM50367548(CHEMBL1794921)
Affinity DataEC50:  50nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014802BDBM50014802(CHEMBL137396 | 4-[Bis-(4-chloro-phenyl)-imidazol-1...)
Affinity DataEC50:  50nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014750BDBM50014750(CHEMBL137049 | 3-[Bis-(4-chloro-phenyl)-imidazol-1...)
Affinity DataEC50:  50nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014324BDBM50014324(CHEMBL29669 | 5-[Bis-(4-chloro-phenyl)-methyl]-pyr...)
Affinity DataEC50:  55nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014324BDBM50014324(CHEMBL29669 | 5-[Bis-(4-chloro-phenyl)-methyl]-pyr...)
Affinity DataEC50:  55nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014793BDBM50014793(CHEMBL137584 | 5-[Bis-(4-chloro-phenyl)-imidazol-1...)
Affinity DataEC50:  57nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014749BDBM50014749(CHEMBL336708 | 3-[Bis-(4-chloro-phenyl)-imidazol-1...)
Affinity DataEC50:  61nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024481BDBM50024481((4-Chloro-phenyl)-pyrimidin-5-yl-(4-trifluoromethy...)
Affinity DataEC50:  66nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014781BDBM50014781(CHEMBL137002 | 1-[(2-Methoxy-phenyl)-phenyl-methyl...)
Affinity DataEC50:  66nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014815BDBM50014815(CHEMBL29904 | Bis-(4-chloro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  71nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014815BDBM50014815(CHEMBL29904 | Bis-(4-chloro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  71nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014752BDBM50014752(CHEMBL133145 | 1-[Bis-(2-chloro-phenyl)-methyl]-1H...)
Affinity DataEC50:  76nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024516BDBM50024516(5-[Bis-(4-chloro-phenyl)-fluoro-methyl]-pyrimidine...)
Affinity DataEC50:  78nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024524BDBM50024524(5-[1,1-Bis-(4-chloro-phenyl)-ethyl]-pyrimidine | C...)
Affinity DataEC50:  82nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014794BDBM50014794(CHEMBL415725 | 3-[Bis-(4-chloro-phenyl)-methyl]-py...)
Affinity DataEC50:  84nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014798BDBM50014798(CHEMBL335836 | Bis-(4-chloro-phenyl)-pyridin-4-yl-...)
Affinity DataEC50:  84nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014791BDBM50014791(CHEMBL334999 | Bis-(4-chloro-phenyl)-(1H-pyrazol-3...)
Affinity DataEC50:  90nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014774BDBM50014774(CHEMBL336616 | Bis-(4-chloro-phenyl)-pyrazin-2-yl-...)
Affinity DataEC50:  94nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014788BDBM50014788(CHEMBL336638 | 1-Benzhydryl-1H-imidazole)
Affinity DataEC50:  125nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024513BDBM50024513(6-Acetylsulfanyl-8-[2-[(4-amino-2-methyl-pyrimidin...)
Affinity DataEC50:  140nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014751BDBM50014751(CHEMBL133026 | 3-[1,1-Bis-(4-chloro-phenyl)-ethyl]...)
Affinity DataEC50:  145nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
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