Compile Data Set for Download or QSAR
Report error Found 73 of affinity data for UniProtKB/TrEMBL: P43378
TargetTyrosine-protein phosphatase non-receptor type 9 [277-582](Human)
Indiana University Research and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 231167BDBM231167(US9340574, 7)
Affinity DataKi:  34nM IC50: 75nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 9 [277-582](Human)
Indiana University Research and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 231166BDBM231166(US9340574, 5)
Affinity DataIC50: 270nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50531902BDBM50531902(CHEMBL4569405)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436358BDBM50436358(CHEMBL2396718)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant PTP-MEG2 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9 [277-582](Human)
Indiana University Research and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 231165BDBM231165(US9340574, 3)
Affinity DataIC50: 900nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 199180BDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425815BDBM50425815(CHEMBL2316908)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425808BDBM50425808(CHEMBL2316906)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50531903BDBM50531903(CHEMBL4530344)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436357BDBM50436357(CHEMBL2396719)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant PTP-MEG2 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425818BDBM50425818(CHEMBL2316905)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425806BDBM50425806(CHEMBL2316907)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425807BDBM50425807(CHEMBL2316902)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425816BDBM50425816(CHEMBL2316910)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50531901BDBM50531901(CHEMBL4540813)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425809BDBM50425809(CHEMBL2316896)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425810BDBM50425810(CHEMBL2316895)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425811BDBM50425811(CHEMBL2316894)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425819BDBM50425819(CHEMBL2316904)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425814BDBM50425814(CHEMBL2311593)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031906BDBM50031906(CHEMBL3360905)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425813BDBM50425813(CHEMBL2316897)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524069BDBM50524069(CHEMBL4454177)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human MEG2 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524068BDBM50524068(CHEMBL4453288)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human MEG2 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524067BDBM50524067(CHEMBL4514865)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human MEG2 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425820BDBM50425820(CHEMBL2316903)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425817BDBM50425817(CHEMBL2316909)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544440BDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544431BDBM50544431(CHEMBL4637459 | US11192850, Entry 4k)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335895BDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of PTP-Meg2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031908BDBM50031908(CHEMBL3360906)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343147BDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MEG2 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343142BDBM50343142(N-(4-butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MEG2 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112357BDBM50112357(CHEMBL3609375)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphatase activity of human Meg2 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112358BDBM50112358(CHEMBL3609374)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphatase activity of human Meg2 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544427BDBM50544427(CHEMBL4632818 | US11192850, Entry 4g)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343148BDBM50343148(N1-(1-(4-(4-fluorophenyl)piperazin-1-yl)-1-(thioph...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MEG2 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112356BDBM50112356(CHEMBL3609373)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphatase activity of human Meg2 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 53072BDBM53072(3-Allyl-5-(3-ethyl-3H-benzothiazol-2-ylidene)-2-th...)
Affinity DataIC50: 5.94E+4nMAssay Description:Inhibition of GST-tagged MEG2 (unknown origin) using phospho-EGFR Asp-Ala-Asp-Glu-Tyr[PO3H2]-Leu-Ile-Pro-Gln-Gln-Gly as substrate preincubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343530BDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataIC50: 6.61E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50363857BDBM50363857(CHEMBL1946248)
Affinity DataIC50: 6.86E+4nMAssay Description:Inhibition of human PTP-MEG2 using p-nitrophenol phosphate as substrate incubated for 35 mins prior to substrate addition measured after 30 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498446BDBM50498446(CHEMBL3596431)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of human PTP-Meg2 using pNPP substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031910BDBM50031910(CHEMBL3360908)
Affinity DataIC50: 7.85E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425823BDBM50425823(CHEMBL2316901)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425821BDBM50425821(CHEMBL2316900)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425822BDBM50425822(CHEMBL2316899)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50558461BDBM50558461(CHEMBL4760367)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50558485BDBM50558485(CHEMBL4800195)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425812BDBM50425812(CHEMBL2316898)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50363855BDBM50363855(CHEMBL1946246)
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibition of human PTP-MEG2 using p-nitrophenol phosphate as substrate incubated for 35 mins prior to substrate addition measured after 30 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
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