Compile Data Set for Download or QSAR
maximum 50k data
Found 327 of affinity data for UniProtKB/TrEMBL: P78540
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350311(CHEMBL1812661)
Affinity DataKi:  8.5nMAssay Description:Binding affinity to human arginase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350311(CHEMBL1812661)
Affinity DataKi:  8.5nMAssay Description:Inhibition of human Arg2 at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561046(CHEMBL4790798)
Affinity DataKi: <10nMAssay Description:Inhibition of human Arg2 using L-arginine as substrate after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561045(CHEMBL4758805)
Affinity DataKi: <10nMAssay Description:Inhibition of human Arg2 using L-arginine as substrate after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561034(CHEMBL4244287)
Affinity DataKi:  30nMAssay Description:Inhibition of human Arg2 at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataKi:  51nMAssay Description:Inhibition of arginase 2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataKi:  51nMAssay Description:Inhibition of human Arg2 at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50230418(CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human Arg2 at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50462601(CHEMBL4250607)
Affinity DataKi:  3.22E+5nMAssay Description:Irreversible inhibition of human arginase 2 using thioarginine as substrate measured up to 360 mins by UV micro plate methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50462600(CHEMBL4238387)
Affinity DataKi:  4.37E+5nMAssay Description:Irreversible inhibition of human arginase 2 using thioarginine as substrate measured up to 360 mins by UV micro plate methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561047(CHEMBL4764455)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human Arg2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642313((+)-(R)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642315((+)-(R)-(5-amino-5-(1-(2-oxo-2- (phenethylamino)et...)
Affinity DataIC50:  4nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50547931(CHEMBL4745275)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant arginase 2 expressed in Escherichia coli using thioarginine by Ellman's assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642314((-)-(S)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642312((-)-(S)-(5-amino-5-(1-(2-((4- chlorobenzyl)amino)-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642218((5-amino-5-(1-(2-((4-chlorobenzyl) amino)-2-oxoeth...)
Affinity DataIC50:  7nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642208((5-amino-5-(1-(2-((2-fluorobenzyl)amino)- 2-oxoeth...)
Affinity DataIC50:  8nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561039(CHEMBL4749355 | US11420984, Example 23)
Affinity DataIC50:  10nMAssay Description:Inhibition of human Arg2 by TOGA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM568474(US11420984, Example 24)
Affinity DataIC50:  10nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642316((-)-(S)-(5-amino-5-(1-(2-oxo-2- (phenethylamino)et...)
Affinity DataIC50:  10.2nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642227((5-amino-5-(1-(2-oxo-2-(prop-2-yn-1- ylamino)ethyl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642221((5-Amino-5-(1-(2-oxo-2- (phenethylamino)ethyl)-1H-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50547934(CHEMBL4757930)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant arginase 2 expressed in Escherichia coli using thioarginine by Ellman's assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642273((5-amino-5-(1-(2-((4-chloro-2- fluorobenzyl)amino)...)
Affinity DataIC50:  18.6nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50:  20nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50:  20nMAssay Description:Inhibition of human Arg2 by TOGA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50547935(CHEMBL4753285)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant arginase 2 expressed in Escherichia coli using thioarginine by Ellman's assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50547933(CHEMBL4752391)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant arginase 2 expressed in Escherichia coli using thioarginine by Ellman's assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50439247(CHEMBL2418831)
Affinity DataIC50:  23nMAssay Description:Inhibition of human arginase-2 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50547936(CHEMBL4750174)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant arginase 2 expressed in Escherichia coli using thioarginine by Ellman's assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50547932(CHEMBL4778086)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant arginase 2 expressed in Escherichia coli using thioarginine by Ellman's assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642309((+)-(R)-(5-amino-5-(1-(2-oxo-2-(prop-2- yn-1-ylami...)
Affinity DataIC50:  30nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50439246(CHEMBL2418830)
Affinity DataIC50:  30nMAssay Description:Inhibition of human arginase-2 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50439245(CHEMBL2418991)
Affinity DataIC50:  33nMAssay Description:Inhibition of human arginase-2 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642310((-)-(S)-(5-amino-5-(1-(2-oxo-2-(prop-2- yn-1-ylami...)
Affinity DataIC50:  35nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50439244(CHEMBL2418829)
Affinity DataIC50:  47nMAssay Description:Inhibition of human arginase-2 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50439243(CHEMBL2418998)
Affinity DataIC50:  50nMAssay Description:Inhibition of human arginase-2 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM642289((5-amino-5-(1-(2-((2,3- difluorobenzyl)amino)-2-ox...)
Affinity DataIC50:  56nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50427899(CHEMBL2326090)
Affinity DataIC50:  67nMAssay Description:Inhibition of human recombinant fully active truncated form of arginase 2 overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50439241(CHEMBL2418999)
Affinity DataIC50:  70nMAssay Description:Inhibition of human arginase-2 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50439242(CHEMBL2418828)
Affinity DataIC50:  85nMAssay Description:Inhibition of human arginase-2 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561049(CHEMBL4793482)
Affinity DataIC50:  100nMAssay Description:Inhibition of human Arg2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50595730(CHEMBL5171566)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant human ARG2 expressed in Escherichia coli using L-arginine hydrochloride as substrate incubated for 1 hr by colorimetric ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM290416((3R,4S)-3-amino-1-(2-(biphenyl-4-ylamino)ethyl)-4-...)
Affinity DataIC50:  125nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM290419((3R,4S)-3-amino-4-(3-boronopropyl)-1-((7-(trifluor...)
Affinity DataIC50:  125nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM290420((3R,4S)-3-amino-4-(3-boronopropyl)-1-(7-chloro-1,2...)
Affinity DataIC50:  125nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM290421((3R,4S)-3-amino-1-(2-amino-3-phenylpropyl)-4-(3- b...)
Affinity DataIC50:  125nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM290423((3R,4S)-3-amino-4-(3-boronopropyl)-1-((5,7-dichlor...)
Affinity DataIC50:  125nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM290426((1S,2S,4S)-1-amino-4-(benzylamino)-2-(3- boronopro...)
Affinity DataIC50:  125nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 327 total ) | Next | Last >>
Jump to: