Compile Data Set for Download or QSAR
Report error Found 47 of affinity data for UniProtKB/TrEMBL: Q9WVG5
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199225BDBM199225(US9216998, 8)
Affinity DataIC50: 4nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50443627BDBM50443627(CHEMBL3092450 | US9216998, 5)
Affinity DataIC50: 17nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199219BDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50: 26nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50443625BDBM50443625(CHEMBL3092448 | US9216998, 25)
Affinity DataIC50: 31nMAssay Description:Inhibition of endothelial lipase in mouse cells after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50443625BDBM50443625(CHEMBL3092448 | US9216998, 25)
Affinity DataIC50: 31nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199205BDBM199205(US9216998, 9)
Affinity DataIC50: 36nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199219BDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50: 48nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199226BDBM199226(US9216998, 10)
Affinity DataIC50: 75nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199207BDBM199207(US9216998, 19)
Affinity DataIC50: 87nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50522804BDBM50522804(CHEMBL4437751)
Affinity DataIC50: 94nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199221BDBM199221(US9216998, 3)
Affinity DataIC50: 96nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50458640BDBM50458640(CHEMBL4203934)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant mouse endothelial lipase expressed in HEK293F cells using HDL as substrate pretreated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50522808BDBM50522808(CHEMBL4520847)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199229BDBM199229(US9216998, 27)
Affinity DataIC50: 108nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50522805BDBM50522805(CHEMBL4514272)
Affinity DataIC50: 120nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199209BDBM199209(US9216998, 13)
Affinity DataIC50: 124nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199208BDBM199208(US9216998, 12)
Affinity DataIC50: 131nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199223BDBM199223(US9216998, 6)
Affinity DataIC50: 136nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199216BDBM199216(US9216998, 22)
Affinity DataIC50: 142nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199210BDBM199210(US9216998, 14)
Affinity DataIC50: 162nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 151238BDBM151238(US8987314, B34)
Affinity DataIC50: 190nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199220BDBM199220(US9216998, 1)
Affinity DataIC50: 195nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50506505BDBM50506505(CHEMBL4460376)
Affinity DataIC50: 200nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 151212BDBM151212(US8987314, B3)
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50506498BDBM50506498(CHEMBL4581886)
Affinity DataIC50: 200nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50506506BDBM50506506(CHEMBL4465833)
Affinity DataIC50: 200nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50506504BDBM50506504(CHEMBL4460663)
Affinity DataIC50: 200nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199222BDBM199222(US9216998, 4)
Affinity DataIC50: 205nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199215BDBM199215(US9216998, 21)
Affinity DataIC50: 237nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 319015BDBM319015(US10173991, Example 57 | N-[(cyclopropyl- carbamoy...)
Affinity DataIC50: 290nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50522805BDBM50522805(CHEMBL4514272)
Affinity DataIC50: 310nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasma using D31-POPC-HDL as substrate incubated for 2 hrs by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 151303BDBM151303(US8987314, B101)
Affinity DataIC50: 320nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199218BDBM199218(US9216998, 24)
Affinity DataIC50: 340nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199217BDBM199217(US9216998, 23)
Affinity DataIC50: 346nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50433475BDBM50433475(CHEMBL2381067)
Affinity DataIC50: 470nMAssay Description:Inhibition of mouse EL expressed in HEK293 cells using PED-A1 as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199214BDBM199214(US9216998, 20)
Affinity DataIC50: 479nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 319014BDBM319014(US10173991, Example 56 | N-[(cyclopropyl- carbamoy...)
Affinity DataIC50: 600nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199228BDBM199228(US9216998, 26)
Affinity DataIC50: 618nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199206BDBM199206(US9216998, 15)
Affinity DataIC50: 677nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50433472BDBM50433472(CHEMBL2381069)
Affinity DataIC50: 680nMAssay Description:Inhibition of mouse EL expressed in HEK293 cells using PED-A1 as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199211BDBM199211(US9216998, 16)
Affinity DataIC50: 1.00E+3nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199227BDBM199227(US9216998, 11)
Affinity DataIC50: 1.20E+3nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199213BDBM199213(US9216998, 18)
Affinity DataIC50: 1.89E+3nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 199212BDBM199212(US9216998, 17)
Affinity DataIC50: 3.62E+3nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50522805BDBM50522805(CHEMBL4514272)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of hepatic lipase in endothelial lipase knock-out mouse plasma using D31-POPC-HDL as substrate incubated for 2 hrs by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50433474BDBM50433474(CHEMBL2381068)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of mouse EL expressed in HEK293 cells using PED-A1 as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50443624BDBM50443624(CHEMBL3092449 | US9216998, 28)
Affinity DataIC50: 3.33E+4nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent