BDBM191598 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid (KDM5-C49)::KDM5-C49::KDOAM-20

SMILES: CCN(CCN(C)C)C(=O)CNCc1cc(ccn1)C(O)=O

InChI Key: InChIKey=RGGMVQDDHDCRDM-UHFFFAOYSA-N

Data: 46 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 55 hits for monomerid = 191598   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4A (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2A (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 3A (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4A (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 3B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4A (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6A (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C [1-765] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B [1-755] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	25
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Lysine-specific demethylase 5C [1-789] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	25
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Lysine-specific demethylase 5D [1-760] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	25
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					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A [1-588] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B [1-604] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A [1-1090] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	59	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A [1-1090] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A [1-801] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A [1-739] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	25
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Lysine-specific demethylase 5D [1-775] (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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Lysine-specific demethylase 4C (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
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					More data for this Ligand-Target Pair
Lysine-specific demethylase 3A (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	780	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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Lysine-specific demethylase 2A (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.5	n/a
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					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM191598 (KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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