BDBM50186231 (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid::CHEMBL456::ETHACRYNIC ACID::Edecrin::Etacrinic acid::Ethacrynate::Hydromedin::Methylenebutyrylphenoxyacetic acid::[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid::jm5b01461, Compound 72

SMILES: CCC(=C)C(=O)c1ccc(c(c1Cl)Cl)OCC(=O)O

InChI Key: InChIKey=AVOLMBLBETYQHX-UHFFFAOYSA-N

Data: 2 KI  25 IC50

PDB links: 10 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50186231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Co-chaperonin GroES (Escherichia coli)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutathione S-transferase P (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucose 4-epimerase (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hematopoietic prostaglandin D synthase (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.22E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutathione S-transferase Mu 2 (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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glutathione transferase (Schistosoma japonicum)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutathione S-transferase A1 (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutathione S-transferase P (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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14 kDa phosphohistidine phosphatase (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 6 (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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60 kDa heat shock protein, mitochondrial (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Chaperonin GroEL (Escherichia coli)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Large T antigen (SV40)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Thiosulfate sulfurtransferase (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Co-chaperonin GroES (Escherichia coli)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutathione S-transferase omega-1 (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Glutathione S-transferase P (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glutathione S-transferase E2 (African malaria mosquito)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	6.5	30
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Perilipin-5 (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Perilipin-1 (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
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14 kDa phosphohistidine phosphatase (Human)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		1.83E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM50186231 ([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...) Show SMILES Show InChI	GoogleScholar	UniChem		3.75E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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