Affinity DataKi: 0.190nM ΔG°: -54.9kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.260nM ΔG°: -54.2kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nM ΔG°: -52.9kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.470nM ΔG°: -52.7kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.560nM ΔG°: -52.3kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -52.1kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.610nM ΔG°: -52.1kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nM ΔG°: -51.7kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.720nM ΔG°: -51.7kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.830nM ΔG°: -51.3kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.920nM ΔG°: -51.1kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nM ΔG°: -49.4kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nM ΔG°: -49.3kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nM ΔG°: -48.8kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nM ΔG°: -48.8kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nM ΔG°: -48.2kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.2kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nM ΔG°: -48.1kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 6.70nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Binding affinity of the compound was tested against caspase-3 (Csp-3)More data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 7.40nM ΔG°: -45.9kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nM ΔG°: -45.8kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 7.90nM ΔG°: -45.8kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 9.20nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 9.20nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 9.40nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 11.1nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
Affinity DataKi: 12nM ΔG°: -44.8kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 12.2nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 12.7nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 12.8nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 13.1nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Institut FüR Pharmazeutische And Medizinische Chemie Der UniversitäT MüüNster
Curated by ChEMBL
Affinity DataKi: 14.9nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair