Affinity DataKi: 0.000350nMAssay Description:Binding affinity to CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.00110nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00110nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00280nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00280nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00530nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.00530nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.00570nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00600nMAssay Description:Antagonist activity on agonist (U50,488) stimulated [35S]GTP-gamma-S, binding in cloned opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataKi: 0.00650nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.00650nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.00700nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.00700nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.00790nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00790nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00900nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding to Opioid receptor mu 1 in Guinea pig caudate st...More data for this Ligand-Target Pair
Affinity DataKi: 0.0160nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Inhibition of stimulation of [35S]GTP-gamma-S, binding produced by the selective agonist (U69593, kappa-receptor), in guinea pig caudate membranes.More data for this Ligand-Target Pair
Affinity DataKi: 0.0210nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding to Opioid receptor mu 1 in Guinea pig caudate st...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0260nMAssay Description:Displacement of [3H]epibatidine from alpha-4-beta-2 nAChRMore data for this Ligand-Target Pair
Affinity DataKi: 0.0260nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding to Opioid receptor mu 1 in Guinea pig caudate st...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.More data for this Ligand-Target Pair
Affinity DataKi: 0.0340nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0380nMAssay Description:Displacement of [3H]epibatidine from alpha-4-beta-2 nAChRMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0380nMAssay Description:Inhibition of stimulation of [35S]GTP-gamma-S, binding produced by the selective agonist (U69593, kappa-receptor), in guinea pig caudate membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0380nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding from Opioid receptor kappa 1 in Guinea pig Caudate stimulated by U69,593More data for this Ligand-Target Pair
Affinity DataKi: 0.0383nMAssay Description:The compound was tested for binding activity against muscarinic acetylcholine receptor M1, using [3H]QNB as the radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.0390nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding from Opioid receptor mu 1 in Guinea pig Caudate stimulated by DAMGOMore data for this Ligand-Target Pair
Affinity DataKi: 0.0390nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding to Opioid receptor mu 1 in Guinea pig caudate st...More data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Displacement of [3H]-substance P from rat NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0460nM ΔG°: -59.0kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor transfected in HN9.10 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0520nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0520nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0530nMAssay Description:Inhibition of [3H]U-69593 binding to Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0540nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 0.0660nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:[3H]-Cl-DPDPE competition binding assay using human cloned opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 0.0750nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0750nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0770nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0820nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0840nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0880nMAssay Description:Inhibition of [3H]QNB binding to CHO cells bearing transfected muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataKi: 0.0890nMAssay Description:Displacement of [3H]substance P from rat NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair