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Report error Found 102 of affinity data for UniProtKB/TrEMBL: P07813
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458119BDBM50458119(Leusa)
Affinity DataKi:  0.139nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Leucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458122BDBM50458122(CHEMBL4204314)
Affinity DataKi:  0.654nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Leucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286772BDBM50286772(CHEMBL4160841)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to Escherichia coli LeuRS by isothermal titration calorimetric calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630400BDBM630400(US11802110, Compound 4.20)
Affinity DataKd:  1.39nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630392BDBM630392(US11802110, Compound R-4.12)
Affinity DataKd:  1.48nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630391BDBM630391(US11802110, Compound 4.11)
Affinity DataKd:  2.17nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569962BDBM50569962(CHEMBL4864835)
Affinity DataKi:  2.5nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630399BDBM630399(US11802110, Compound 4.19)
Affinity DataKd:  3.35nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630404BDBM630404(US11802110, Compound 4.27)
Affinity DataKd:  3.69nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630176BDBM630176(US11802110, Compound R-4.1)
Affinity DataKd:  3.86nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630394BDBM630394(US11802110, Compound 4.14)
Affinity DataKd:  4.02nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630397BDBM630397(US11802110, Compound 4.17)
Affinity DataKd:  4.47nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630407BDBM630407(US11802110, Compound 4.32)
Affinity DataKd:  4.61nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569952BDBM50569952(CHEMBL4869028)
Affinity DataKi:  5.5nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630398BDBM630398(US11802110, Compound 4.18)
Affinity DataKd:  6.06nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630401BDBM630401(US11802110, Compound 4.21)
Affinity DataKd:  6.61nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630393BDBM630393(US11802110, Compound 4.13)
Affinity DataKd:  6.62nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630406BDBM630406(US11802110, Compound 4.31)
Affinity DataKd:  6.78nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630405BDBM630405(US11802110, Compound 4.29)
Affinity DataKd:  9.14nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524359BDBM50524359(CHEMBL4465674)
Affinity DataKi:  9.80nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286770BDBM50286770(CHEMBL4171058)
Affinity DataKd:  10nMAssay Description:Displacement of IK-698 from Escherichia coli LeuRS by isothermal titration calorimetric calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286766BDBM50286766(CHEMBL4163450)
Affinity DataKd:  10nMAssay Description:Displacement of IK-698 from Escherichia coli LeuRS by isothermal titration calorimetric calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630395BDBM630395(US11802110, Compound 4.15)
Affinity DataKd:  10.6nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286774BDBM50286774(CHEMBL4163140)
Affinity DataKd:  11nMAssay Description:Displacement of IK-698 from Escherichia coli LeuRS by isothermal titration calorimetric calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630410BDBM630410(US11802110, Compound 4.39)
Affinity DataKd:  12.8nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286774BDBM50286774(CHEMBL4163140)
Affinity DataIC50: 13nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286767BDBM50286767(CHEMBL4172643)
Affinity DataKd:  13nMAssay Description:Displacement of IK-698 from Escherichia coli LeuRS by isothermal titration calorimetric calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286767BDBM50286767(CHEMBL4172643)
Affinity DataIC50: 14nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286765BDBM50286765(CHEMBL4159778)
Affinity DataKd:  14nMAssay Description:Displacement of IK-698 from Escherichia coli LeuRS by isothermal titration calorimetric calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286769BDBM50286769(CHEMBL4161986)
Affinity DataKd:  15nMAssay Description:Displacement of IK-698 from Escherichia coli LeuRS by isothermal titration calorimetric calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630409BDBM630409(US11802110, Compound 4.35)
Affinity DataKd:  16.4nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630403BDBM630403(US11802110, Compound 4.23)
Affinity DataKd:  17.5nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569957BDBM50569957(CHEMBL4864965)
Affinity DataKi:  18nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524355BDBM50524355(CHEMBL4467328)
Affinity DataKi:  21nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286771BDBM50286771(CHEMBL4167692)
Affinity DataKd:  22nMAssay Description:Displacement of IK-698 from Escherichia coli LeuRS by isothermal titration calorimetric calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286765BDBM50286765(CHEMBL4159778)
Affinity DataIC50: 23nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630396BDBM630396(US11802110, Compound 4.16)
Affinity DataKd:  27.2nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524361BDBM50524361(CHEMBL4451258)
Affinity DataKi:  30nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569960BDBM50569960(CHEMBL4852287)
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569963BDBM50569963(CHEMBL4855635)
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569958BDBM50569958(CHEMBL4864716)
Affinity DataKi:  32nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286770BDBM50286770(CHEMBL4171058)
Affinity DataIC50: 32nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 630402BDBM630402(US11802110, Compound 4.22)
Affinity DataKd:  34.5nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286772BDBM50286772(CHEMBL4160841)
Affinity DataIC50: 35nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286766BDBM50286766(CHEMBL4163450)
Affinity DataIC50: 41nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286771BDBM50286771(CHEMBL4167692)
Affinity DataIC50: 47nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569954BDBM50569954(CHEMBL4867227)
Affinity DataKi:  52nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286769BDBM50286769(CHEMBL4161986)
Affinity DataIC50: 54nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286775BDBM50286775(CHEMBL4174152)
Affinity DataKd:  56nMAssay Description:Displacement of IK-698 from Escherichia coli LeuRS by isothermal titration calorimetric calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286768BDBM50286768(CHEMBL4171458)
Affinity DataKd:  64nMAssay Description:Displacement of IK-698 from Escherichia coli LeuRS by isothermal titration calorimetric calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details Article
PubMed
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