BDBM50021574 BMS-907351::CABOZANTINIB::CHEBI:72317::Cabometyx::Cometriq::US10183928, Cabozantinib::US10202365, Compound Cabozantinib::US10227329, Compound Cabozantinib::US10273211, Compound Cabozantinib::US10464902, Cabozantinib::US10774070, Compound Cabozantinib::US11279688, Compound Cabozantinib::XL-184::cabozantinib s-malate
SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC
InChI Key InChIKey=ONIQOQHATWINJY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50021574
Affinity DataIC50: 225nMAssay Description:Inhibition of EGFR (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Hangzhou Xixi Hospital
Curated by ChEMBL
Hangzhou Xixi Hospital
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of KIT (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hangzhou Xixi Hospital
Curated by ChEMBL
Hangzhou Xixi Hospital
Curated by ChEMBL
Affinity DataIC50: 0.0860nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hangzhou Xixi Hospital
Curated by ChEMBL
Hangzhou Xixi Hospital
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of FLT3 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Hangzhou Xixi Hospital
Curated by ChEMBL
Hangzhou Xixi Hospital
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Hangzhou Xixi Hospital
Curated by ChEMBL
Hangzhou Xixi Hospital
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 45 mins by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hangzhou Xixi Hospital
Curated by ChEMBL
Hangzhou Xixi Hospital
Curated by ChEMBL
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Hangzhou Xixi Hospital
Curated by ChEMBL
Hangzhou Xixi Hospital
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of RET (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Hangzhou Xixi Hospital
Curated by ChEMBL
Hangzhou Xixi Hospital
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by HTRF methodMore data for this Ligand-Target Pair