BDBM50021574 BMS-907351::CABOZANTINIB::CHEBI:72317::Cabometyx::Cometriq::US10183928, Cabozantinib::US10202365, Compound Cabozantinib::US10227329, Compound Cabozantinib::US10273211, Compound Cabozantinib::US10464902, Cabozantinib::US10774070, Compound Cabozantinib::US11279688, Compound Cabozantinib::XL-184::cabozantinib s-malate
SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC
InChI Key InChIKey=ONIQOQHATWINJY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50021574
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human Ret M918T mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human Ret V804L mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 358nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human Ret S891A mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human Ret G691S mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human Ret Y791F mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair