BDBM50366775 BENZTROPINE::Benzatropine
SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(c1ccccc1)c1ccccc1
InChI Key InChIKey=GIJXKZJWITVLHI-PMOLBWCYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50366775
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pipeline Therapeutics
Curated by ChEMBL
Pipeline Therapeutics
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human recombinant muscarinic receptor M3 expressed in CHO-K1 cells assessed as EC80 acetylcholine-induced calcium flux incubat...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Pipeline Therapeutics
Curated by ChEMBL
Pipeline Therapeutics
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human recombinant muscarinic receptor M4 expressed in CHO-K1 cells assessed as EC80 acetylcholine-induced calcium flux incubat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 403nMAssay Description:Inhibition of [3H]dopamine uptake in rat caudate putamen tissue.More data for this Ligand-Target Pair
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in the cynomolgus (macaca fascicularis) monkey caudate-putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 312nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in the cynomolgus (macaca fascicularis) monkey caudate-putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 2.41E+4nMAssay Description:Binding affinity of [3H]citalopram for serotonin transporter in monkeyMore data for this Ligand-Target Pair
Affinity DataIC50: 312nMAssay Description:Displacement of [3H]WIN-35428 from monkey dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Ability to inhibit binding of [3H]WIN-35428 to dopamine transporter in rat caudate putamenMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Pipeline Therapeutics
Curated by ChEMBL
Pipeline Therapeutics
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Antagonist activity at human recombinant muscarinic receptor M2 expressed in CHO-K1 cells assessed as EC80 acetylcholine-induced calcium flux incubat...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 403nMAssay Description:Inhibition of [3H]dopamine uptake in rat caudate putamen.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 403nMAssay Description:[3H]-Dopamine uptake inhibition in rat caudate putamenMore data for this Ligand-Target Pair