Compile Data Set for Download or QSAR
Report error Found 149 Enz. Inhib. hit(s) with Target = 'Low molecular weight protein-tyrosine phosphatase A'
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataKi:  800nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis PtpA assessed as inhibition constant using varying level of pNPP as substrate by Lineweaver-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM84499(CHEMBL1765359 | 2-(5-{1-[(2Z)-2H-pyrrol-2-ylidene]...)
Affinity DataIC50: 900nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466475(CHEMBL4292242)
Affinity DataKi:  1.20E+3nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50464769(CHEMBL4290098)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50341977(2-(2,5-dimethyl-1H-pyrrol-1-yl)-5-hydroxybenzoic a...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50341977(2-(2,5-dimethyl-1H-pyrrol-1-yl)-5-hydroxybenzoic a...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466478(CHEMBL4288744)
Affinity DataKi:  1.70E+3nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50464767(Chalcomoracin)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193719((S)-5,7-dihydroxy-2-(7-hydroxy-2,2-dimethyl-2H-chr...)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466478(CHEMBL4288744)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50544111(CHEMBL4638054)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312266((4-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)pheny...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312260((4-(3,5-bis(trifluoromethyl)phenylcarbamoyl)phenyl...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50650293(CHEMBL5624932)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv ptpA expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50242014(Morusin, 3 | cid_5281671 | Morusin | CHEMBL464006 ...)
Affinity DataIC50: 4.65E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040(1-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312259((4-(4-bromo-3-(trifluoromethyl)phenylcarbamoyl)phe...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193042((2E)-1-(2',5'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466479(CHEMBL4280516)
Affinity DataKi:  5.60E+3nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50464771(CHEMBL4279417)
Affinity DataIC50: 5.89E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312258((4-(4-chloro-3-(trifluoromethyl)phenylcarbamoyl)ph...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466479(CHEMBL4280516)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50331863(6-(4-Hydroxy-benzyl)-9-(phenyl-phenylamino-methyl)...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant protein tyrosine phosphatase A by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193042((2E)-1-(2',5'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193042((2E)-1-(2',5'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM84495(CHEMBL1945189 | Roseophilin, 1)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTP-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50363165(PRODIGIOSIN)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTP-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50606980(CHEMBL5220804)
Affinity DataIC50: 8.97E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpA using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50246224((2E)-1-(2'-hydroxyphenyl)-3-(1-naphthyl)-2-propen-...)
Affinity DataKi:  9.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466482(CHEMBL4282817)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466475(CHEMBL4292242)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312256((4-(4-bromophenylcarbamoyl)phenyl)difluoromethylph...)
Affinity DataKi:  1.03E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312252(difluoro(4-(3-(trifluoromethyl)phenylcarbamoyl)phe...)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312257(difluoro(4-(4-fluoro-3-(trifluoromethyl)phenylcarb...)
Affinity DataKi:  1.14E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50269559(Norartocarpetin, 5 | CHEMBL463145 | 2-(2,4-dihydro...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50363157(CHEMBL1945186)
Affinity DataKi:  1.20E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis PTP-A using p-nitrophenyl phosphate as substrate measured for 10 mins by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466482(CHEMBL4282817)
Affinity DataKi:  1.20E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466476(CHEMBL4279400)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50464768(CHEMBL4291588)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50363157(CHEMBL1945186)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTP-A using p-nitrophenyl phosphate as substrate measured for 10 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466477(CHEMBL4294511)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312255((4-(4-chlorophenylcarbamoyl)phenyl)difluoromethylp...)
Affinity DataKi:  1.68E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466480(CHEMBL4280931)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50320828(1-(3'-methoxy-4'-hydroxyphenyl)-3-(2-naphthyl)-2-p...)
Affinity DataKi:  1.79E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312251((4-(3-bromophenylcarbamoyl)phenyl)difluoromethylph...)
Affinity DataKi:  1.82E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466481(CHEMBL4285399)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50312254(difluoro(4-(4-(trifluoromethyl)phenylcarbamoyl)phe...)
Affinity DataKi:  1.85E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50606979(CHEMBL5219572)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpA using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193009((2E)-1-(2',5'-dimethoxyphenyl)-3-(1-naphthyl)-2-pr...)
Affinity DataKi:  2.13E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
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