Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with Target = 'FKBP12A/mTOR'
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093070BDBM50093070(CHEMBL3586561)
Affinity DataIC50: 4nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093075BDBM50093075(CHEMBL3586566)
Affinity DataIC50: 6nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243950BDBM50243950(CHEMBL4079746)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length recombinant human mTOR/FKBP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092782BDBM50092782(CHEMBL3586387)
Affinity DataIC50: 8nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093080BDBM50093080(CHEMBL3586571)
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093077BDBM50093077(CHEMBL3586568)
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093076BDBM50093076(CHEMBL3586567)
Affinity DataIC50: 12nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093069BDBM50093069(CHEMBL3586560)
Affinity DataIC50: 15nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093074BDBM50093074(CHEMBL3586565)
Affinity DataIC50: 20nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093082BDBM50093082(CHEMBL3586573)
Affinity DataIC50: 23nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093071BDBM50093071(CHEMBL3586562)
Affinity DataIC50: 27nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092783BDBM50092783(CHEMBL3586404)
Affinity DataIC50: 30nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92862BDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 44nMAssay Description:Inhibition of mTORC1 (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093078BDBM50093078(CHEMBL3586569)
Affinity DataIC50: 44nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093081BDBM50093081(CHEMBL3586572)
Affinity DataIC50: 53nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093068BDBM50093068(CHEMBL3586559)
Affinity DataIC50: 54nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093079BDBM50093079(CHEMBL3586570)
Affinity DataIC50: 66nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117874BDBM50117874(CHEMBL3612310)
Affinity DataIC50: 78nMAssay Description:Inhibition of mTORC1 (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093072BDBM50093072(CHEMBL3586563)
Affinity DataIC50: 85nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092781BDBM50092781(CHEMBL3586386)
Affinity DataIC50: 108nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600034BDBM50600034(CHEMBL5194372)
Affinity DataIC50: 125nMAssay Description:Inhibition of human full length recombinant mTOR/FKBP12 in presence of [gamma-33P]ATP incubated for 40 mins by radiometric scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092773BDBM50092773(CHEMBL3586394)
Affinity DataIC50: 200nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093073BDBM50093073(CHEMBL3586564)
Affinity DataIC50: 203nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092770BDBM50092770(CHEMBL3586398)
Affinity DataIC50: 230nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092787BDBM50092787(CHEMBL3585359)
Affinity DataIC50: 240nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092788BDBM50092788(CHEMBL3586381)
Affinity DataIC50: 240nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092768BDBM50092768(CHEMBL3586403)
Affinity DataIC50: 340nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431519BDBM50431519(CHEMBL2348862)
Affinity DataIC50: 390nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092767BDBM50092767(CHEMBL3586402)
Affinity DataIC50: 530nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092779BDBM50092779(CHEMBL3586391)
Affinity DataIC50: 650nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519662BDBM50519662(CHEMBL4438748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human mTOR/FKBP12 measured after 40 mins in presence of [gamma33P]ATP by radiometric scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed