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Found 88 with Last Name = 'takayama' and Initial = 'k'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095997(3',4',7-trihydroxyisoflavone | CHEMBL13486)
Affinity DataKi:  38nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096004(7-Hydroxy-3-[4-(2-oxo-2H-chromen-3-yl)-thiazol-2-y...)
Affinity DataKi:  280nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096003(7-Hydroxy-3-phenyl-chromen-2-one | 7-hydroxy-3-phe...)
Affinity DataKi:  470nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096001(7-Hydroxy-3-pyrazolo[1,5-a]pyridin-2-yl-chromen-2-...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095993(7-Hydroxy-2-oxo-2H-chromene-3-carbothioic acid ami...)
Affinity DataKi:  550nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096002(3-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-7-hydroxy...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096007(2-Oxo-2H-chromene-3-carboxylic acid 2-oxo-2-phenyl...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096006(7-Hydroxy-3-(2-methyl-thiazol-4-yl)-chromen-2-one ...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096000(3-(2-Fluoro-4-hydroxy-phenyl)-acrylic acid anion)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095994(3-Cyano-7-hydroxycoumarin (2) | 7-Hydroxy-2-oxo-2H...)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096005(7-Hydroxy-3-(4-methyl-thiazol-2-yl)-chromen-2-one ...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096008(3-Acetyl-7-hydroxy-chromen-2-one | 3-acetyl-7-hydr...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095996(3-(7-Hydroxy-2-oxo-2H-chromen-3-yl)-3-oxo-propioni...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50096009(3-(4-Dimethylamino-benzylidene)-chroman-2,4-dione ...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095995(7-HYDROXY-2-OXO-CHROMENE-3-CARBOXYLIC ACID ETHYL E...)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50608178(CHEMBL5268044)
Affinity DataIC50:  0.890nMAssay Description:Photo-oxygenation mediated inactivation of human recombinant Myostatin expressed in Escherichia coli cells photoirradiated for 30 mins using LED foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50608179(CHEMBL5285634)
Affinity DataIC50:  2.10nMAssay Description:Photo-oxygenation mediated inactivation of human recombinant Myostatin expressed in Escherichia coli cells photoirradiated for 30 mins using LED foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50539387(CHEMBL4648474)
Affinity DataIC50:  130nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells incubated for 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50525413(CHEMBL4448117)
Affinity DataIC50:  130nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells incubated for 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314672(2-(3-bromophenyl)-4-(pyridin-3-ylmethylene)oxazol-...)
Affinity DataIC50:  148nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314673(2-(2-bromo-4-methoxyphenyl)-4-(pyridin-3-ylmethyle...)
Affinity DataIC50:  157nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50585028(CHEMBL5078185)
Affinity DataIC50:  190nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50585028(CHEMBL5078185)
Affinity DataIC50:  190nMAssay Description:Photo-oxygenation mediated inactivation of human recombinant Myostatin expressed in Escherichia coli cells photoirradiated for 30 mins using LED foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314664(2-(2-chloro-5-iodophenyl)-4-(pyridin-4-ylmethylene...)
Affinity DataIC50:  227nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50525413(CHEMBL4448117)
Affinity DataIC50:  260nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50537170(CHEMBL4516740)
Affinity DataIC50:  260nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314665(2-(4-chloro-3-nitrophenyl)-4-(pyridin-3-ylmethylen...)
Affinity DataIC50:  279nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314670(2-(4-bromo-3-methylphenyl)-4-(pyridin-3-ylmethylen...)
Affinity DataIC50:  279nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50254771(CHEMBL4061416)
Affinity DataIC50:  290nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells incubated for 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314671(2-(4-nitrophenyl)-4-(pyridin-3-ylmethylene)oxazol-...)
Affinity DataIC50:  291nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50585029(CHEMBL5092917)
Affinity DataIC50:  300nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50254771(CHEMBL4061416)
Affinity DataIC50:  320nMAssay Description:Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314668(2-(3,4-difluorophenyl)-4-(pyridin-3-ylmethylene)ox...)
Affinity DataIC50:  346nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314669(2-(3-chlorophenyl)-4-(pyridin-3-ylmethylene)oxazol...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50254771(CHEMBL4061416)
Affinity DataIC50:  360nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314674(2-(3-methoxyphenyl)-4-(pyridin-3-ylmethylene)oxazo...)
Affinity DataIC50:  395nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314667(2-(4-chlorophenyl)-4-(pyridin-3-ylmethylene)oxazol...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314675(2-(4-methyl-3-nitrophenyl)-4-(pyridin-3-ylmethylen...)
Affinity DataIC50:  534nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314663(2-phenyl-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one...)
Affinity DataIC50:  583nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50314666(4-(pyridin-3-ylmethylene)-2-m-tolyloxazol-5(4H)-on...)
Affinity DataIC50:  714nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50206029(CHEMBL3892004)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50206029(CHEMBL3892004)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant myostatin expressed in HEK293 cells after 4 hrs by SBE4 based luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50030766(CHEMBL3342339)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of porcine tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50585028(CHEMBL5078185)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of TGF beta 1 (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50030765(NPI-2358 | Plinabulin)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of porcine tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50525413(CHEMBL4448117)
Affinity DataIC50:  3.56E+3nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells incubated for 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50071380(CHEMBL3410232)
Affinity DataIC50:  3.56E+3nMAssay Description:Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50071379(CHEMBL3410227)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human recombinant myostatin pre-incubated with compound for 1 hr before addition to human HepG2 cells assessed as reduction in myostati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50539386(CHEMBL4646947)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells incubated for 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50525413(CHEMBL4448117)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of TGF beta 1 (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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