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Found 42 with Last Name = 'bottazzi' and Initial = 'me'
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50143320((+)-epibatidine | (-)-1-epidatidine | (1S,2S,4R)-2...)
Affinity DataKi:  0.0450nMAssay Description:Binding affinity to alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114372(CHEMBL3604279)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain membrane without cerebellum by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114370(CHEMBL3604281)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114373(CHEMBL3604278)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114371(CHEMBL3604280)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114369(CHEMBL3604282)
Affinity DataKi:  9.10nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50195530(5-(4-chlorophenyl)-3-[(E)-2-cyclohexylethenyl]-1-(...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain membrane without cerebellum by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50429403(CHEMBL2337204)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain membrane without cerebellum by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50429405(CHEMBL2337206)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain membrane without cerebellum by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127648(CHEMBL3628495)
Affinity DataKi:  73nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50429404(CHEMBL2337205)
Affinity DataKi:  175nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain membrane without cerebellum by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127655(CHEMBL3628496)
Affinity DataKi:  176nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114370(CHEMBL3604281)
Affinity DataKi:  183nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50429401(CHEMBL2337202)
Affinity DataKi:  287nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain membrane without cerebellum by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114372(CHEMBL3604279)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  375nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleen membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50429402(CHEMBL2337203)
Affinity DataKi:  412nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain membrane without cerebellum by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114369(CHEMBL3604282)
Affinity DataKi:  950nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114373(CHEMBL3604278)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50429403(CHEMBL2337204)
Affinity DataKi:  1.95E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleen membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114371(CHEMBL3604280)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50429405(CHEMBL2337206)
Affinity DataKi:  2.23E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleen membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114371(CHEMBL3604280)
Affinity DataKi:  2.27E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114370(CHEMBL3604281)
Affinity DataKi:  2.45E+3nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50195530(5-(4-chlorophenyl)-3-[(E)-2-cyclohexylethenyl]-1-(...)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleen membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114372(CHEMBL3604279)
Affinity DataKi:  3.83E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114373(CHEMBL3604278)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50429402(CHEMBL2337203)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleen membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50429404(CHEMBL2337205)
Affinity DataKi:  4.20E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleen membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Istituto Di Farmacologia Traslazionale

Curated by ChEMBL
LigandPNGBDBM50114369(CHEMBL3604282)
Affinity DataKi:  4.25E+3nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in mouse brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Neuroscienze Pharmaness S.C.A R.L.

Curated by ChEMBL
LigandPNGBDBM50429401(CHEMBL2337202)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleen membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127663(CHEMBL3628504)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127662(CHEMBL3628503)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127665(CHEMBL3628506)
Affinity DataKi:  6.50E+3nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127660(CHEMBL3628501)
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127656(CHEMBL3628497)
Affinity DataKi:  1.70E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127659(CHEMBL3628500)
Affinity DataKi:  3.40E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127661(CHEMBL3628502)
Affinity DataKi:  3.60E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127657(CHEMBL3628498)
Affinity DataKi:  4.80E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127664(CHEMBL3628505)
Affinity DataKi:  9.60E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Sassari

Curated by ChEMBL
LigandPNGBDBM50127658(CHEMBL3628499)
Affinity DataKi:  1.10E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed