Affinity DataKi: 0.148nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from rat histamine H3 receptor expressed in HEK293 cells after 45 mins by liquid scintillation spectromet...More data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.363nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.676nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from rat histamine H3 receptor expressed in HEK293 cells after 45 mins by liquid scintillation spectromet...More data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.832nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from rat histamine H3 receptor expressed in HEK293 cells after 45 mins by liquid scintillation spectromet...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:Displacement of [3H]pyrilamine from human H1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 3.98nMAssay Description:Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 4.68nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in Sprague-Dawley rat cortical membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 5.01nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.01nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.37nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in Sprague-Dawley rat cortical membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.62nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in Sprague-Dawley rat cortical membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 6.31nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Displacement of [3H]pyrilamine from human H1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Displacement of [3H]pyrilamine from human H1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.71nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in Sprague-Dawley rat cortical membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair