BindingDB PrimarySearch

Found 53 with Last Name = 'friggeri' and Initial = 'l'

Lanosterol 14-alpha demethylase(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM213825(VNI)

IC50: 250nMAssay Description:Inhibition of Candida albicans CYP51 assessed as reduction in [3-3H]lanosterol 14alpha-demethylation preincubated for 60 secs followed by NADPH addit...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505763(CHEMBL4466288)

IC50: <500nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 min using [3H] lanosterol as substrate by HPLC analys...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505758(CHEMBL4444489)

PDB Reactome pathway
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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505765(CHEMBL4435160)

PDB Reactome pathway
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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505766(CHEMBL4522116)

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3D Structure (crystal)

Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50465948(CHEMBL3629567)

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3D Structure (crystal)

Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505764(CHEMBL4461447)

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505768(CHEMBL4439225)

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505761(CHEMBL4277680)

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505765(CHEMBL4435160)

IC50: <1.00E+3nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysi...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505766(CHEMBL4522116)

PDB Reactome pathway
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3D Structure (crystal)

Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505760(CHEMBL4458275)

IC50: 1.50E+3nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 min using [3H] lanosterol as substrate by HPLC analys...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505759(CHEMBL4593688)

IC50: 3.00E+3nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 min using [3H] lanosterol as substrate by HPLC analys...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505768(CHEMBL4439225)

IC50: 3.60E+3nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysi...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505764(CHEMBL4461447)

IC50: 4.40E+3nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysi...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505762(CHEMBL4452294)

IC50: 5.20E+3nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 min using [3H] lanosterol as substrate by HPLC analys...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505761(CHEMBL4277680)

IC50: 5.90E+3nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysi...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505767(CHEMBL4472919)

IC50: 1.20E+4nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 min using [3H] lanosterol as substrate by HPLC analys...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505758(CHEMBL4444489)

IC50: 1.50E+4nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysi...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505763(CHEMBL4466288)

IC50: 1.90E+4nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysi...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50465948(CHEMBL3629567)

IC50: 2.44E+4nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysi...More data for this Ligand-Target Pair

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3D Structure (crystal)

Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505759(CHEMBL4593688)

IC50: >2.50E+4nMAssay Description:Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysi...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505767(CHEMBL4472919)

PDB Reactome pathway
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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505762(CHEMBL4452294)

PDB Reactome pathway
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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505760(CHEMBL4458275)

PDB Reactome pathway
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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505766(CHEMBL4522116)

Kd: 90nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

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3D Structure (crystal)

Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505762(CHEMBL4452294)

Kd: 3.90E+3nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50465948(CHEMBL3629567)

PDB Reactome pathway
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3D Structure (crystal)

Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505768(CHEMBL4439225)

Kd: 130nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

PDB Reactome pathway
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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505767(CHEMBL4472919)

Kd: 2.32E+3nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505765(CHEMBL4435160)

Kd: 150nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

PDB Reactome pathway
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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505764(CHEMBL4461447)

Kd: 20nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

PDB Reactome pathway
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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505763(CHEMBL4466288)

Kd: 2.50E+3nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

PDB Reactome pathway
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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505761(CHEMBL4277680)

Kd: 60nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

PDB Reactome pathway
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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505760(CHEMBL4458275)

Kd: 1.65E+3nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505759(CHEMBL4593688)

Kd: 1.15E+3nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50505758(CHEMBL4444489)

Kd: 470nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair

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Putative lanosterol 14-alpha-demethylase(Leishmania infantum)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50465948(CHEMBL3629567)

Kd: 8.40nMAssay Description:Binding affinity to Leishmania infantum CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair

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Putative lanosterol 14-alpha-demethylase(Leishmania infantum)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM213825(VNI)

Kd: 2nMAssay Description:Binding affinity to Leishmania infantum CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair

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Putative lanosterol 14-alpha-demethylase(Leishmania infantum)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50276214(CHEMBL4129161)

Kd: 1.70nMAssay Description:Binding affinity to Leishmania infantum CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair

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Sterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50276214(CHEMBL4129161)

Kd: 4.20nMAssay Description:Binding affinity to Trypanosoma cruzi Y CYP51A expressed in Escherichia coliMore data for this Ligand-Target Pair

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Sterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50465949(CHEMBL4276822)

Kd: 8.40nMAssay Description:Binding affinity to Trypanosoma cruzi Y CYP51A expressed in Escherichia coliMore data for this Ligand-Target Pair

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Putative lanosterol 14-alpha-demethylase(Leishmania infantum)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50465949(CHEMBL4276822)

Kd: 24nMAssay Description:Binding affinity to Leishmania infantum CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair

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Sterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50465948(CHEMBL3629567)

Kd: 6.80nMAssay Description:Binding affinity to Trypanosoma cruzi Y CYP51A expressed in Escherichia coliMore data for this Ligand-Target Pair

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3D Structure (crystal)

Sterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM213825(VNI)

Kd: 8.30nMAssay Description:Binding affinity to Trypanosoma cruzi Y CYP51A expressed in Escherichia coliMore data for this Ligand-Target Pair

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3D Structure (crystal)

Lanosterol 14-alpha demethylase(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50181473(4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)met...)

Kd: 81nMAssay Description:Binding affinity to Candida albicans CYP51 by spectral titration methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Lanosterol 14-alpha demethylase(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50276219(CHEMBL4126063)

Kd: 95nMAssay Description:Binding affinity to Candida albicans CYP51 by spectral titration methodMore data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50276218(CHEMBL4128615)

Kd: 25nMAssay Description:Binding affinity to Candida albicans CYP51 by spectral titration methodMore data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50276215(CHEMBL4128885)

Kd: 10nMAssay Description:Binding affinity to Candida albicans CYP51 by spectral titration methodMore data for this Ligand-Target Pair

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Lanosterol 14-alpha demethylase(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
Vanderbilt University School Of Medicine

Curated by ChEMBL

BDBM50276214(CHEMBL4129161)

Kd: 13nMAssay Description:Binding affinity to Candida albicans CYP51 by spectral titration methodMore data for this Ligand-Target Pair

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