TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.0726nMAssay Description:Displacement of [3H]PK11195 from rat PBR receptorMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.0726nMAssay Description:Binding affinity to PBR in Sprague-Dawley rat mitochondrial tissueMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by microbeta scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.0978nMAssay Description:Binding affinity to PBR in Sprague-Dawley rat mitochondrial tissueMore data for this Ligand-Target Pair
Affinity DataKi: 0.101nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by microbeta scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.106nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by microbeta scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.137nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by microbeta scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by microbeta scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]PK11195 from rat PBR receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.231nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by microbeta scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.242nMAssay Description:Binding affinity to PBR in human mitochondrial tissueMore data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.242nMAssay Description:Displacement of [3H]PK11195 from human PBR receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.253nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by microbeta scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Binding affinity to rat brain CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.299nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity to mGluR1 by PET analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat striata 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat striata 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.590nMAssay Description:Cell membrane was prepared from CRTH2-expressing K562 cell. The cell membrane (20 μg/well) was mixed with reaction buffer (50 mM Tris/HCl, pH 7....More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [11C]-PK-11195 from TPSO in Sprague-Dawley rat brain homogenate after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair