Found 94 with Last Name = 'jerman' and Initial = 'jc' 
Affinity DataKi: 2.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 269nMAssay Description:Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 316nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 631nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 631nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.98E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: <5.01E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.01E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: <6.31E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 1.58E+4nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
Affinity DataKi: <3.16E+4nMAssay Description:Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]- SB-204269 displacement.More data for this Ligand-Target Pair
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 6.61E+4nMAssay Description:Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometryMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity against human TRPV1 assessed as inhibition of acid-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 9nMpH: 5.3Assay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5.3 acid-induced calcium influx by whole cell patch clamp a...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 40nMpH: 5.3Assay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5.3 acid-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium influx by whole cell patch clamp ass...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Cavia porcellus)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 63nMpH: 5.3Assay Description:Antagonist activity at guinea pig TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5.3 acid-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 100nMpH: 5.3Assay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5.3 acid-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+4nMAssay Description:Inhibition of cytochrome P450 1A2More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+4nMAssay Description:Inhibition of cytochrome P450 2D6More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+4nMAssay Description:Inhibition of cytochrome P450 2C9More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+4nMAssay Description:Inhibition of cytochrome P450 2C19More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+4nMAssay Description:Inhibition of cytochrome P450 3A4More data for this Ligand-Target Pair
