Affinity DataKi: 0.160nMAssay Description:Antagonist activity at recombinant human H3 receptor expressed in CHO-K1 cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Zhengzhou University
Curated by ChEMBL
Zhengzhou University
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Competitive inhibition of PLK-4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Binding affinity to N-terminal GST tagged recombinant DCN5 (unknown origin) (47 to 237 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Zhengzhou University
Curated by ChEMBL
Zhengzhou University
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of PLK-4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 6.34nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 9.07nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 9.35nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibition of constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity to N-terminal GST tagged recombinant human DCN1 (58 to 259 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction i...More data for this Ligand-Target Pair
Affinity DataKi: 15.0nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human DCN1 expressed in Escherichia coli BL21-AI assessed as reduction in DCN1-FAM-labelled N-...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Zhengzhou University
Curated by ChEMBL
Zhengzhou University
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Reversible inhibition of wild-type human SHP2 using DiFMUP as substrate and measured by jump dilution assayMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Dissociation constant against galectin-3 using competitive fluorescence polarizationMore data for this Ligand-Target Pair
Affinity DataKi: 29.2nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 50.4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 66nMAssay Description:Binding affinity to N-terminal GST tagged recombinant DCN2 (unknown origin) (62 to 259 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Zhengzhou University
Curated by ChEMBL
Zhengzhou University
Curated by ChEMBL
Affinity DataKi: 67nMAssay Description:Reversible inhibition of wild-type human SHP2 using DiFMUP as substrate and measured by jump dilution assayMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Inhibition of androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Inhibition of androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 193nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)More data for this Ligand-Target Pair
Affinity DataKi: 247nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 273nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
Affinity DataKi: 560nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...More data for this Ligand-Target Pair
Affinity DataKi: 592nMAssay Description:Binding affinity to N-terminal GST tagged recombinant DCN3 (unknown origin) (86 to 304 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...More data for this Ligand-Target Pair
Affinity DataKi: 807nMAssay Description:Binding affinity to N-terminal GST tagged recombinant DCN4 (unknown origin) (102 to 292 residues) expressed in Escherichia coli BL21(DE3) assessed as...More data for this Ligand-Target Pair
Affinity DataKi: 810nMAssay Description:Binding affinity to DCN4 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4(diMe) peptide as substrate measured after 60 mins by amplex red dye based HRP-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
Affinity DataKi: 2.14E+3nMAssay Description:Binding affinity to DCN5 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...More data for this Ligand-Target Pair
Affinity DataKi: 2.94E+3nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair