Affinity DataKi: 2.70nM ΔG°: -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nM ΔG°: -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nM ΔG°: -48.8kJ/mole IC50: 30nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/mole IC50: 37nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
TargetRocR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Competitive binding affinity to Pseudomonas aeruginosa PAO1 His6-tagged RocR expressed in Escherichia coli BL21 (DE3) after 5 mins in presence of [32...More data for this Ligand-Target Pair
TargetRocR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Competitive binding affinity to Pseudomonas aeruginosa PAO1 His6-tagged RocR expressed in Escherichia coli BL21 (DE3) after 5 mins in presence of [32...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 180nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:A coupled spectrophotometric assay was used, wherein ADP generated by Syk kinase was converted to ATP by pyruvate kinase (PK), with concomitant produ...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair