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Found 115 with Last Name = 'shapiro' and Initial = 'ab'
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50200120(CHEMBL260091 | CHIR-090 | US10875832, Compound ChI...)
Affinity DataIC50: <1nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231666(N-(2-(1H-indol-3-yl)ethyl)-3-(3-thiazol-2-ylureido...)
Affinity DataIC50:  2.20nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231665(1-(3-(4-(Pyridin-2-yl)piperazin-1-ylsulfonyl)pheny...)
Affinity DataIC50:  2.70nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50:  7nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231666(N-(2-(1H-indol-3-yl)ethyl)-3-(3-thiazol-2-ylureido...)
Affinity DataIC50:  13nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50:  18nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231665(1-(3-(4-(Pyridin-2-yl)piperazin-1-ylsulfonyl)pheny...)
Affinity DataIC50:  22nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50:  23nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554708(CHEMBL4746493)
Affinity DataIC50:  37nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554707(CHEMBL4751248)
Affinity DataIC50:  44nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554702(CHEMBL4776055)
Affinity DataIC50:  45nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50:  58nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231670(5-(3-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol...)
Affinity DataIC50:  60nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554703(CHEMBL4798753)
Affinity DataIC50:  63nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554700(CHEMBL4786538)
Affinity DataIC50:  64nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231674(N-(2-(1-(methylsulfonyl)cyclopropyl)ethyl)-2-(3-(5...)
Affinity DataIC50:  70nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231671(Ethyl 2-(3-(5-(trifluoromethyl)-1H-pyrazol-3-yl)ph...)
Affinity DataIC50:  80nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231669(2-[3-[(4-Chloro-2-pyridyl)amino]phenoxy]-N-(1,1-di...)
Affinity DataIC50:  100nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231676(2-((4-Chlorophenoxy)methyl)-N-(cyanomethyl)thiazol...)
Affinity DataIC50:  100nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554704(CHEMBL4755244)
Affinity DataIC50:  170nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231677(2-((4-Chlorophenoxy)methyl)-N-(2-sulfamoylethyl)th...)
Affinity DataIC50:  190nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554709(CHEMBL4755307)
Affinity DataIC50:  280nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50:  280nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50:  400nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50365095(CHEMBL1951184)
Affinity DataIC50:  500nMAssay Description:Inhibition of Streptococcus pneumoniae acetyltransferase activity of GlmU using acetyl-CoA and glucosamine-1-phosphate after 30 mins by Ellman's meth...More data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231668(2-(3-(4-Cyanopyridin-2-ylamino)phenoxy)-N-methylac...)
Affinity DataIC50:  560nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554725(CHEMBL4780225)
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554724(CHEMBL4786712)
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554723(CHEMBL4758871)
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554722(CHEMBL4776397)
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554717(CHEMBL4746231)
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554706(CHEMBL4761278)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554705(CHEMBL4796789)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231672(Ethyl 2-(3-(3-(difluoromethyl)-1H-pyrazol-5-yl)phe...)
Affinity DataIC50:  1.00E+3nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554701(CHEMBL4760055)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554713(CHEMBL4794466)
Affinity DataIC50:  1.30E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231667(2-(3-(4-Chloropyridin-2-ylamino)phenoxy)-N-methyla...)
Affinity DataIC50:  1.40E+3nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231675(N-(1,1-dioxothiolan-3-yl)-2-[(4-methylphenoxy)meth...)
Affinity DataIC50:  1.40E+3nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50365097(CHEMBL1951186)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Streptococcus pneumoniae acetyltransferase activity of GlmU using acetyl-CoA and glucosamine-1-phosphate after 30 mins by Ellman's meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50365098(CHEMBL1951187)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Streptococcus pneumoniae acetyltransferase activity of GlmU using acetyl-CoA and glucosamine-1-phosphate after 30 mins by Ellman's meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM50365062(CHEMBL1951072 | Sulfonamide, 1)
Affinity DataIC50:  2.10E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554712(CHEMBL4779531)
Affinity DataIC50:  2.40E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM50365075(CHEMBL1951164 | Sulfonamide, 2)
Affinity DataIC50:  3.30E+3nM Kd:  1.90E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554717(CHEMBL4746231)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human AchE expressed in HEK293 cells using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231674(N-(2-(1-(methylsulfonyl)cyclopropyl)ethyl)-2-(3-(5...)
Affinity DataIC50:  4.20E+3nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50:  4.70E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50365094(CHEMBL1951183)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Streptococcus pneumoniae acetyltransferase activity of GlmU using acetyl-CoA and glucosamine-1-phosphate after 30 mins by Ellman's meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554714(CHEMBL4741753)
Affinity DataIC50:  5.40E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM50365075(CHEMBL1951164 | Sulfonamide, 2)
Affinity DataIC50:  6.40E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554715(CHEMBL4753921)
Affinity DataIC50:  7.30E+3nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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