Compile Data Set for Download or QSAR
maximum 50k data
Found 300 with Last Name = 'wilhelm' and Initial = 's'
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588336(CHEMBL5186739)
Affinity DataKi:  51nMAssay Description:Antagonist activity at human alpha5beta2gamma2 GABAA receptor expressed in HEK cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588336(CHEMBL5186739)
Affinity DataKi:  79nMAssay Description:Antagonist activity at human alpha3beta2gamma2 GABAA receptor expressed in HEKcells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588336(CHEMBL5186739)
Affinity DataKi:  88nMAssay Description:Antagonist activity at recombinant human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  195nMAssay Description:Antagonist activity at human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588337(CHEMBL5177970)
Affinity DataKi:  290nMAssay Description:Antagonist activity at human alpha3beta2gamma2 GABAA receptor expressed in HEKcells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588336(CHEMBL5186739)
Affinity DataKi:  320nMAssay Description:Antagonist activity at human alpha2beta2gamma2 GABAA receptor expressed in HEK cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  540nMAssay Description:Antagonist activity at human alpha5beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  560nMAssay Description:Antagonist activity at human alpha3beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588337(CHEMBL5177970)
Affinity DataKi:  590nMAssay Description:Antagonist activity at human alpha5beta2gamma2 GABAA receptor expressed in HEK cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588336(CHEMBL5186739)
Affinity DataKi:  790nMAssay Description:Antagonist activity at human alpha1beta2gamma2 GABAA receptor expressed in HEK by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588337(CHEMBL5177970)
Affinity DataKi:  1.03E+3nMAssay Description:Antagonist activity at recombinant human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588340(CHEMBL5204910)
Affinity DataKi:  1.28E+3nMAssay Description:Antagonist activity at human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588340(CHEMBL5204910)
Affinity DataKi:  1.50E+3nMAssay Description:Antagonist activity at human alpha5beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  2.18E+3nMAssay Description:Antagonist activity at human alpha1beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588337(CHEMBL5177970)
Affinity DataKi:  2.96E+3nMAssay Description:Antagonist activity at human alpha2beta2gamma2 GABAA receptor expressed in HEK cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588340(CHEMBL5204910)
Affinity DataKi:  3.57E+3nMAssay Description:Antagonist activity at human alpha3beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588338(CHEMBL5186559)
Affinity DataKi:  4.57E+3nMAssay Description:Displacement of [3H]-muscimol from human GABAA alpha1beta3gamma2 stably expressed in Ltk cells assessed as inhibition constant by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  4.95E+3nMAssay Description:Antagonist activity at human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588337(CHEMBL5177970)
Affinity DataKi:  4.96E+3nMAssay Description:Antagonist activity at human alpha1beta2gamma2 GABAA receptor expressed in HEK by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588337(CHEMBL5177970)
Affinity DataKi:  6.68E+3nMAssay Description:Antagonist activity at recombinant human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  7.56E+3nMAssay Description:Antagonist activity at human alpha2beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588340(CHEMBL5204910)
Affinity DataKi:  1.00E+4nMAssay Description:Antagonist activity at human alpha1beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588340(CHEMBL5204910)
Affinity DataKi:  1.32E+4nMAssay Description:Antagonist activity at human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588340(CHEMBL5204910)
Affinity DataKi:  2.53E+4nMAssay Description:Antagonist activity at human alpha2beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588336(CHEMBL5186739)
Affinity DataKi:  6.02E+4nMAssay Description:Antagonist activity at recombinant human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50451624(CHEMBL331897)
Affinity DataIC50:  0.580nMAssay Description:Binding affinity was determined towards C-C chemokine receptor type 3 using [125I]-labeled eotaxin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50451624(CHEMBL331897)
Affinity DataIC50:  0.900nMAssay Description:Binding affinity towards C-C chemokine receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215791(2-((2-acetamidopyridin-4-yl)methylamino)-N-(2,2-di...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50091927(1-(2,6-Dichloro-phenyl)-1-(4'-fluoro-6-hydroxymeth...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2 expressed in E. coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215766(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50099482(2-(6-Amino-benzothiazol-2-ylsulfanyl)-N-[1-(3,4-di...)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity was determined towards C-C chemokine receptor type 3 using [125I]-labeled eotaxin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50133793(1-{(S)-1-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50:  2.40nMAssay Description:Compound was tested for its ability to inhibit C-C chemokine receptor type 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215788(CHEMBL399534 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215761(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215793(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215774(CHEMBL246424 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215758(2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215759(CHEMBL247423 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215758(2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215770(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50114250(1-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-3-(4-pyr...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human epidermal growth factor receptor-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50133792(1-{(S)-1-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50:  4.40nMAssay Description:Compound was tested for its ability to inhibit C-C chemokine receptor type 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50133796(1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50:  4.70nMAssay Description:Compound was tested for its ability to inhibit C-C chemokine receptor type 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215773(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215761(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215791(2-((2-acetamidopyridin-4-yl)methylamino)-N-(2,2-di...)
Affinity DataIC50:  5nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215775(1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50100021((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Affinity DataIC50:  5nMAssay Description:Binding affinity was determined towards C-C chemokine receptor type 3 using [125I]-labeled eotaxin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase [305-648](Homo sapiens (Human))
Bayer Pharmaceuticals

LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  6nMpH: 8.2 T: 2°CAssay Description:The biochemical activity of compound was determined by incubation with Raf kinases and substrate MEK-1 in the presence of 1-10 uM ATP/ [gamma-32P] AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095409(5-tert-Butyl-3-[3-(2,3-dichloro-phenyl)-ureido]-1H...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 300 total ) | Next | Last >>
Jump to: