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Found 1398 with Last Name = 'xue' and Initial = 'l'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174361(CHEMBL370606 | L-888607 | [(S)-9-(4-Chloro-phenyls...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407800(CHEMBL5291138)
Affinity DataKi:  16nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174354(CHEMBL373294 | [1-(2,5-Dichloro-benzenesulfonyl)-5...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174357(CHEMBL199040 | [1-(4-Chloro-benzenesulfonyl)-5-flu...)
Affinity DataKi:  29nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346870(CHEMBL1797647)
Affinity DataKi:  40nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataKi:  50nMAssay Description:In vitro binding affinity (agonistic) towards human CRTH2 receptor expressed in CHO cells; range 15 to 25 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50346870(CHEMBL1797647)
Affinity DataKi:  50nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174351(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Affinity DataKi:  68nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Shanghai University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50552232(CHEMBL4776624)
Affinity DataKi:  68nMAssay Description:Mixed inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174352(CHEMBL370257 | [5-Fluoro-1-(4-fluoro-benzenesulfon...)
Affinity DataKi:  71nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586363(CHEMBL5079374)
Affinity DataKi:  140nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50407795(CHEMBL5281080)
Affinity DataKi:  157nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50407796(CHEMBL1255711)
Affinity DataKi:  193nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50407722(CHEMBL5287743)
Affinity DataKi:  210nMAssay Description:Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151161(5-Phenyl-1H-pyrrole-2-carboxylic acid (1-cyclohexy...)
Affinity DataKi:  220nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174353(CHEMBL196617 | [5-Fluoro-1-(3-fluoro-benzenesulfon...)
Affinity DataKi:  225nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174358((1-Benzenesulfonyl-5-fluoro-2-methyl-1H-indol-3-yl...)
Affinity DataKi:  250nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151159(5-Phenyl-1H-pyrrole-2-carboxylic acid (1-cyclohexy...)
Affinity DataKi:  280nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174360(CHEMBL364299 | [5-Fluoro-1-(4-methoxy-benzenesulfo...)
Affinity DataKi:  299nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50568522(CHEMBL4864352)
Affinity DataKi:  370nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174356(CHEMBL193753 | [5-Fluoro-2-methyl-1-(toluene-4-sul...)
Affinity DataKi:  457nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chembridge Research Laboratories And Chembridge

Curated by ChEMBL
LigandPNGBDBM50181669(5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50346586(CHEMBL1795981 | US8765820, 5a)
Affinity DataKi:  500nMAssay Description:Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50568521(CHEMBL4878787)
Affinity DataKi:  560nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346585(CHEMBL1795980 | S2101)
Affinity DataKi:  610nMAssay Description:Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174359(CHEMBL194918 | [1-(Butane-1-sulfonyl)-5-fluoro-2-m...)
Affinity DataKi:  634nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151163(5-Phenyl-1H-pyrrole-2-carboxylic acid (1-cyclohexy...)
Affinity DataKi:  870nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346585(CHEMBL1795980 | S2101)
Affinity DataKi:  880nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151168(5-Phenyl-1H-pyrrole-2-carboxylic acid (cyclohexylc...)
Affinity DataKi:  910nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chembridge Research Laboratories And Chembridge

Curated by ChEMBL
LigandPNGBDBM50181675(5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibitory activity against ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50346863(CHEMBL1797640 | US8765820, 5b)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151160(5-Phenyl-1H-pyrrole-2-carboxylic acid (3-diethylam...)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151169(5-Phenyl-1H-pyrrole-2-carboxylic acid [1-cyclohexy...)
Affinity DataKi:  1.17E+3nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151158(5-Phenyl-1H-pyrrole-2-carboxylic acid (1-tert-buty...)
Affinity DataKi:  1.18E+3nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50346864(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151167(5-Phenyl-1H-pyrrole-2-carboxylic acid [cyclohexylc...)
Affinity DataKi:  1.29E+3nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50346864(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151164(5-Phenyl-1H-pyrrole-2-carboxylic acid [cyclohexylc...)
Affinity DataKi:  1.32E+3nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151157(5-Phenyl-1H-pyrrole-2-carboxylic acid [cyclohexylc...)
Affinity DataKi:  1.37E+3nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Shanghai University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human CES2A using 4-methylumbelliferone as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50158869(CHEMBL3786182 | US10836743, Compound GSK-2879552 |...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4(diMe) peptide as substrate measured after 60 mins by amplex red dye based HRP-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174354(CHEMBL373294 | [1-(2,5-Dichloro-benzenesulfonyl)-5...)
Affinity DataKi:  1.87E+3nMAssay Description:Binding affinity towards human DP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50346586(CHEMBL1795981 | US8765820, 5a)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151165(5-Phenyl-1H-pyrrole-2-carboxylic acid (1-cyclohexy...)
Affinity DataKi:  1.92E+3nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151170(CHEMBL185887 | N-[Cyclohexylcarbamoyl-(4-fluoro-ph...)
Affinity DataKi:  2.03E+3nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407723(CHEMBL5274037)
Affinity DataKi:  2.30E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50346863(CHEMBL1797640 | US8765820, 5b)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Institute For Life Science Research

Curated by ChEMBL
LigandPNGBDBM50151166(5-Phenyl-1H-pyrrole-2-carboxylic acid [cyclohexylc...)
Affinity DataKi:  2.63E+3nMAssay Description:Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174355(CHEMBL194019 | [1-(1,2-Dimethyl-1H-imidazole-4-sul...)
Affinity DataKi:  2.98E+3nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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