TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 10.9nMAssay Description:Binding Affinity to cocaine site of dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]-mazindol .More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibition of [3H]NE uptake at Norepinephrine transporter in rat parietal/occipital cortex was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Inhibition of [3H]NE uptake at Norepinephrine transporter in rat parietal/occipital cortex was determinedMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Inhibition of [3H]-DA Uptake at dopamine transporter in rat cortex was measured by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 67nMAssay Description:Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Inhibition of [3H]NE uptake at Norepinephrine transporter in rat parietal/occipital cortex was determinedMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 71nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 79nMAssay Description:Affinity to displace binding of [3H]WIN-35428 to dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 86nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 99nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 99nMAssay Description:Affinity to displace binding of [3H]WIN-35428 to dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 108nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 108nMAssay Description:Inhibition of [3H]DA uptake evaluated at the dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 108nMAssay Description:Inhibition of [3H]-NE Uptake in rat parietal/occipital cortexMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 124nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 124nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 141nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of [3H]NE uptake at Norepinephrine transporter in rat parietal/occipital cortex was determinedMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 155nMAssay Description:Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 155nMAssay Description:Inhibition of [3H]-5-HT Uptake in rat mid brain.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 155nMAssay Description:Inhibition of [3H]-5-HT uptake evaluated at the Serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Inhibition of [3H]5-HT uptake at Serotonin transporter in rat mid brainMore data for this Ligand-Target Pair
Affinity DataKi: 177nMAssay Description:Compound was tested for Inhibition of [3H]-NE Uptake in rat parietal/occipital cortexMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 189nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Inhibition of [3H]DA uptake at Dopamine transporter in rat cortex.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of reuptake of DA into striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of [3H]DA uptake at Dopamine transporter in rat cortex.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 225nMAssay Description:Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of [3H]5-HT uptake at Serotonin transporter in rat mid brainMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 231nMAssay Description:Binding Affinity to Dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]-mazindol .More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 255nMAssay Description:Inhibition of [3H]DA uptake evaluated at the dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 263nMAssay Description:Inhibition of [3H]DA uptake evaluated at the dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 270nMAssay Description:Affinity to inhibit [3H]DA uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 270nMAssay Description:Inhibition of [3H]DA uptake at Dopamine transporter in rat cortex.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 274nMAssay Description:Inhibition of [3H]-DA Uptake was measured by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 274nMAssay Description:Compound was tested for the inhibition of [3H]DA reuptake into rat striatal tissueMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 360nMAssay Description:Inhibition of [3H]-DA Uptake at Dopamine transporter in rat cortex was measured by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Inhibition of [3H]5-HT uptake at Serotonin transporter in rat mid brainMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 393nMAssay Description:Inhibition of [3H]-NE uptake evaluated at the monoamine transporter (NET)More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 398nMAssay Description:Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 424nMAssay Description:Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:Inhibition of [3H]NE uptake at Norepinephrine transporter in rat parietal/occipital cortex was determinedMore data for this Ligand-Target Pair