Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 30 hits in this display
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
IC50: 8.30nMAssay Description:Inhibition of N-terminal FLAG-tagged wild type BRAF (unknown origin) expressed in baculovirus system using GST-MEK1(K96R) as substrate after 20 minsMore data for this Ligand-Target Pair
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
IC50: 120nMAssay Description:Inhibition of PDGFR beta (unknown origin) using biotinylated poly-Glu-Tyr (4:1) as substrate preincubated for 5 mins measured after 12 hrsMore data for this Ligand-Target Pair
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
IC50: 610nMAssay Description:Inhibition of PDGFR alpha (unknown origin) using biotinylated poly-Glu-Tyr (4:1) as substrate preincubated for 5 mins measured after 12 hrsMore data for this Ligand-Target Pair
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
IC50: 3.70E+3nMAssay Description:Inhibition of C-terminal FLAG-tagged IKK beta (unknown origin) expressed in baculovirus system using IkappaBalpha as substrate after 40 minsMore data for this Ligand-Target Pair
BDBM99471(US8497274, 32)
IC50: >1.00E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged MEKK1 (unknown origin) expressed in baculovirus system using MBP as substrate after 60 minsMore data for this Ligand-Target Pair
Pirin(Homo sapiens (Human))The Institute Of Cancer Research
Curated by ChEMBL
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
IC50: >1.00E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged ERK1 expressed in baculovirus system (unknown origin) using MBP as substrate after 60 minsMore data for this Ligand-Target Pair
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
IC50: <1.00E+4nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
IC50: >1.00E+4nMAssay Description:Inhibition of c-Met receptor (unknown origin) using biotinylated poly-Glu-Tyr (4:1) as substrate preincubated for 5 mins measured after 12 hrsMore data for this Ligand-Target Pair
BDBM99471(US8497274, 32)
IC50: >1.00E+4nMAssay Description:Inhibition of Insulin receptor (unknown origin) using biotinylated poly-Glu-Tyr (4:1) as substrate preincubated for 5 mins measured after 12 hrsMore data for this Ligand-Target Pair
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)
BDBM99471(US8497274, 32)